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Found 15 Enz. Inhib. hit(s) with all data for entry = 1352
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317578(US9624198, 3 | [4-(3,4-Dihydroisoquinolin-2(1H)-yl...)
Affinity DataIC50:  9nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317586(US9624198, 11 | US9624198, 12 | [4-(3,4-Dihydroiso...)
Affinity DataIC50:  11nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317585(US9624198, 10 | [4-(3,4-Dihydroisoquinolin-2(1H)-y...)
Affinity DataIC50:  11nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317584(US9624198, 9 | [4-(6-Methoxy-3,4-dihydroisoquinoli...)
Affinity DataIC50:  11nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317577(US9624198, 2 | [4-(7-Fluoro-3,4-dihydroisoquinolin...)
Affinity DataIC50:  13nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317586(US9624198, 11 | US9624198, 12 | [4-(3,4-Dihydroiso...)
Affinity DataIC50:  21nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317582(US9624198, 7 | [4-(3,4-Dihydroisoquinolin-2(1H)-yl...)
Affinity DataIC50:  21nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317576( [4-(3,4-Dihydroisoquinolin-2-(1H)-yl)piperidin-1-...)
Affinity DataIC50:  22nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317589(US9624198, 14 | [4-(3,4-Dihydroisoquinolin-2(1H)-y...)
Affinity DataIC50:  23nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317579(US9624198, 4 | [4-(3,4-Dihydroisoquinolin-2(1H)-yl...)
Affinity DataIC50:  24nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317581(1-(5-{[4-(3,4-Dihydroisoquinolin-2(1H)-yl)piperidi...)
Affinity DataIC50:  27nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317588(US9624198, 13 | [4-(3,4-Dihydroisoquinolin-2(1H)-y...)
Affinity DataIC50:  53nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317590(US9624198, 15 | [4-(3,4-Dihydroisoquinolin-2(1H)-y...)
Affinity DataIC50:  53nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317583(US9624198, 8 | [4-(6-Fluoro-3,4-dihydroisoquinolin...)
Affinity DataIC50:  58nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM317580(US9624198, 5 | [4-(3,4-Dihydroisoquinolin-2(1H)-yl...)
Affinity DataIC50:  65nMAssay Description:Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent