Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 1478
TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325758BDBM325758((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  2nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325774BDBM325774((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-5,...)
Affinity DataEC50:  5nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325766BDBM325766((rac)-N-Cyclopropyl-2-[4-[2-fluoro-4-(trifluoromet...)
Affinity DataEC50:  6nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325772BDBM325772((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  6nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325761BDBM325761((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  8nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325751BDBM325751((rac)-Ethyl 2-[4-[3-fluoro-4-(trifluoromethyl)phen...)
Affinity DataEC50:  9nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325758BDBM325758((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  10nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325762BDBM325762((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  10nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325775BDBM325775((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-5,...)
Affinity DataEC50:  11nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325771BDBM325771((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  12nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325753BDBM325753((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  13nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325755BDBM325755((rac)-N-Cyclopropyl-2-[4-[3-fluoro-4-(trifluoromet...)
Affinity DataEC50:  13nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325752BDBM325752((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  17nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325760BDBM325760((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  17nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325765BDBM325765((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  18nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325759BDBM325759((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  20nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325754BDBM325754((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  21nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325756BDBM325756((rac)-N-(Cyclopropylmethyl)-2-[4-[3-fluoro-4-(trif...)
Affinity DataEC50:  24nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325773BDBM325773((rac)-Ethyl 2-[4-[2-fluoro-4-(trifluoromethyl)phen...)
Affinity DataEC50:  27nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325767BDBM325767((rac)-N-Cyclopropyl-N-ethyl-2-[4-[2-fluoro-4-(trif...)
Affinity DataEC50:  29nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325761BDBM325761((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  30nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325757BDBM325757((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  32nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325776BDBM325776((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-5,...)
Affinity DataEC50:  32nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325778BDBM325778( (+)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-5,6...)
Affinity DataEC50:  36nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325781BDBM325781((rac)-N-Cyclopropyl-2-[4-[2-fluoro-4-(trifluoromet...)
Affinity DataEC50:  37nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325764BDBM325764((rac)-N-Ethyl-2-[4-[2-fluoro-4-(trifluoromethyl)ph...)
Affinity DataEC50:  44nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325769BDBM325769((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  45nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325768BDBM325768((rac)-1-(Azetidin-1-yl)-2-[4-[2-fluoro-4-(trifluor...)
Affinity DataEC50:  48nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325770BDBM325770((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  53nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325763BDBM325763((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  67nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325753BDBM325753((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  69nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325782BDBM325782((rac)-N-(Cyclopropylmethyl)-2-[4-[2-fluoro-4-(trif...)
Affinity DataEC50:  71nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325751BDBM325751((rac)-Ethyl 2-[4-[3-fluoro-4-(trifluoromethyl)phen...)
Affinity DataEC50:  84nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325774BDBM325774((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-5,...)
Affinity DataEC50:  85nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325754BDBM325754((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  112nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325779BDBM325779((-)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-5,6,...)
Affinity DataEC50:  133nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325759BDBM325759((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  152nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325760BDBM325760((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  180nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325762BDBM325762((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  194nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325752BDBM325752((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  199nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325766BDBM325766((rac)-N-Cyclopropyl-2-[4-[2-fluoro-4-(trifluoromet...)
Affinity DataEC50:  211nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325780BDBM325780((rac)-N-Ethyl-2-[4-[2-fluoro-4-(trifluoromethyl)ph...)
Affinity DataEC50:  212nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325755BDBM325755((rac)-N-Cyclopropyl-2-[4-[3-fluoro-4-(trifluoromet...)
Affinity DataEC50:  217nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325783BDBM325783((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-5,...)
Affinity DataEC50:  222nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325772BDBM325772((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  278nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325756BDBM325756((rac)-N-(Cyclopropylmethyl)-2-[4-[3-fluoro-4-(trif...)
Affinity DataEC50:  331nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325781BDBM325781((rac)-N-Cyclopropyl-2-[4-[2-fluoro-4-(trifluoromet...)
Affinity DataEC50:  448nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325771BDBM325771((rac)-2-[4-[2-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  507nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325757BDBM325757((rac)-2-[4-[3-Fluoro-4-(trifluoromethyl)phenyl]-6,...)
Affinity DataEC50:  582nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 325767BDBM325767((rac)-N-Cyclopropyl-N-ethyl-2-[4-[2-fluoro-4-(trif...)
Affinity DataEC50:  745nMAssay Description:G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-200...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

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