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Found 21 Enz. Inhib. hit(s) with all data for entry = 1499
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327436(N-(3-{(1R,5S,6r)-3-[3-(1-ethoxy-4,4-difluorocycloh...)
Affinity DataIC50:  1.30nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327443(N-{3-[(1R,5S)-6-ethyl-3-azabicyclo[3.1.0]hexan-6-y...)
Affinity DataIC50:  1.30nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327428( N-(3-{(1R,5S,6r)-3-[3-(4,4-difluoro-1-methoxycycl...)
Affinity DataIC50:  1.30nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327429(N-(3-{(1R,5S,6r)-3-[3-(4,4-difluoropiperidin-1-yl)...)
Affinity DataIC50:  1.40nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327423( N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-hydroxy-2,3-dihydr...)
Affinity DataIC50:  1.5nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327426(N-(3-{(1R,5S,6r)-3-[3-(4,4-difluorocyclohexyl)prop...)
Affinity DataIC50:  1.5nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327427(N-(3-{(1R,5S,6r)-3-[3-(4,4-difluorocyclohexyl)prop...)
Affinity DataIC50:  1.60nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327437(N-(3-{(1R,5S,6r)-3-[3-(4,4-difluoropiperidin-1-yl)...)
Affinity DataIC50:  1.70nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327424(N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-hydroxy-2,3-dihydro...)
Affinity DataIC50:  2nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327431(N-(3-{(1R,5S,6r)-3-[3-(3,3-difluoropyrrolidin-1-yl...)
Affinity DataIC50:  2.5nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327433(N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-methoxy-2,3-dihydro...)
Affinity DataIC50:  2.80nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327430(N-(3-{(1R,5S,6r)-3-[3-(3,3-difluoropyrrolidin-1-yl...)
Affinity DataIC50:  2.90nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327438(N-(3-{(1R,5S,6r)-3-[3-(3,3-difluoropiperidin-1-yl)...)
Affinity DataIC50:  3.10nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327432(N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-hydroxy-2,3-dihydro...)
Affinity DataIC50:  3.20nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327425(N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-methoxy-2,3-dihydro...)
Affinity DataIC50:  3.60nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327442(N-(3-{(1R,5S,6r)-3-[(5,6-difluoro-2-hydroxy-2,3-di...)
Affinity DataIC50:  4.10nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327435(N-(3-{(1R,5S,6r)-3-[(2-ethoxy-2,3-dihydro-1H-inden...)
Affinity DataIC50:  4.10nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327441(N-(3-{(1R,5S,6r)-3-[(2-hydroxy-2,3-dihydro-1H-inde...)
Affinity DataIC50:  4.5nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327439(N-(3-{(1R,5S,6r)-3-[(2-hydroxy-2,3-dihydro-1H-inde...)
Affinity DataIC50:  5.40nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327434(N-(3-{(1R,5S,6r)-6-ethyl-3-[(2-methoxy-2,3-dihydro...)
Affinity DataIC50:  12nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Sanwa Kagaku Kenkyusho

US Patent
LigandPNGBDBM327440(N-(3-{(1R,5S,6r)-3-[(2-methoxy-2,3-dihydro-1H-inde...)
Affinity DataIC50:  16nMAssay Description:The inhibition ratio of the test substance at the respective concentrations were calculated with setting the reaction value of the well to which DMSO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent