Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 134
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187124(US9670161, 5 N-{6-(Difluoromethyl)-4-[(methylsulfo...)
Affinity DataIC50: 1nMpH: 8.0Assay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187120(US9670161, 1 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 2nMpH: 8.0Assay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187124(US9670161, 5 N-{6-(Difluoromethyl)-4-[(methylsulfo...)
Affinity DataIC50: 2nMpH: 8.0Assay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187120(US9670161, 1 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 2nMpH: 8.0Assay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187122(US9670161, 3 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 2nMpH: 8.0Assay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187121(US9670161, 2 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 2nMpH: 8.0Assay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187123(US9670161, 4 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 3nMpH: 8.0Assay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187122(US9670161, 3 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 3nMpH: 8.0Assay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187121(US9670161, 2 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 3nMpH: 8.0Assay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187123(US9670161, 4 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 4nMpH: 8.0Assay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187124(US9670161, 5 N-{6-(Difluoromethyl)-4-[(methylsulfo...)
Affinity DataIC50: 7nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187123(US9670161, 4 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 52nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187122(US9670161, 3 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 65nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187121(US9670161, 2 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 70nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187124(US9670161, 5 N-{6-(Difluoromethyl)-4-[(methylsulfo...)
Affinity DataIC50: 103nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187123(US9670161, 4 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 169nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187120(US9670161, 1 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 170nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187121(US9670161, 2 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 625nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187122(US9670161, 3 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 787nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM187120(US9670161, 1 5-Fluoro-4-(4-fluoro-2-methoxyphenyl)...)
Affinity DataIC50: 2.18E+3nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent