Compile Data Set for Download or QSAR
Report error Found 138 Enz. Inhib. hit(s) with all data for entry = 138
TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187784(US9670193, 36 3-chloro-N-(1-(pyridin-4-yl)ethyl)-5...)
Affinity DataIC50: 6.40nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187643(US9670193, 35 3-chloro-N-(pyridin-4-ylmethyl)-5-(5...)
Affinity DataIC50: 11nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187543(US9670193, 21 (R)-N-(1-(benzyl(methyl)amino)propan...)
Affinity DataIC50: 18nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187802(US9670193, 37 3-chloro-N-(pyridin-3-ylmethyl)-5-(5...)
Affinity DataIC50: 19nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187232(US9670193, 15 N-(1-(pyridin-4-yl)propyl)-5-(5-(tri...)
Affinity DataIC50: 20nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187803(US9670193, 38 3-Chloro-N-((6-methylpyridin-3-yl)me...)
Affinity DataIC50: 21nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187219(US9670193, 9 N-(1-(pyridin-4-yl)ethyl)-5-(5-(trifl...)
Affinity DataIC50: 22nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187223(US9670193, 13 (R)-N-(1-phenylpropyl)-5-(5-(trifluo...)
Affinity DataIC50: 22nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187218(US9670193, 8 N-((6-methylpyridin-3-yl)methyl)-5-(5...)
Affinity DataIC50: 25nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187628(US9670193, 29 N-(1-phenylethyl)-5-(5-(trifluoromet...)
Affinity DataIC50: 27nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187565(US9670193, 23 (R)-N-(1-(diethylamino)propan-2-yl)-...)
Affinity DataIC50: 28nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM188028(US9670193, 44 (R)-N-(Pyridin-4-yl)ethyl)-5-(5-trif...)
Affinity DataIC50: 29nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187244(US9670193, 17 N-methyl-N-((2-methylpyridin-4-yl)me...)
Affinity DataIC50: 34nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187213(US9670193, 4 N-benzyl-5-(5-(trifluoromethyl)-1,2,4...)
Affinity DataIC50: 36nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187804(US9670193, 39 3-chloro-N-(pyridin-2-ylmethyl)-5-(5...)
Affinity DataIC50: 37nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187187(US9670193, 3 N-methyl-N-(pyridin-4-ylmethyl)-5-(5-...)
Affinity DataIC50: 39nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187214(US9670193, 5 N-((2-chloropyridin-4-yl)methyl)-N-me...)
Affinity DataIC50: 40nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187638(US9670193, 31 N-(pyridin-4-ylmethyl)-5-(5-(trifluo...)
Affinity DataIC50: 41nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187215(US9670193, 6 N-(pyridin-4-ylmethyl)-5-(5-(trifluor...)
Affinity DataIC50: 44nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187242(US9670193, 16 N-(1-(2-methylpyridin-4-yl)ethyl)-5-...)
Affinity DataIC50: 44nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187642(US9670193, 34 (R)-3-chloro-N-(1-phenylethyl)-5-(5-...)
Affinity DataIC50: 47nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187222(US9670193, 12 (R)-N-(1-phenylethyl)-5-(5-(trifluor...)
Affinity DataIC50: 49nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM188006(US9670193, 41 (R)-N-(1-Phenylethyl)-2-(5-(trifluor...)
Affinity DataIC50: 60nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187639(US9670193, 32 N-((6-methylpyridin-3-yl)methyl)-5-(...)
Affinity DataIC50: 63nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM188029(US9670193, 45 (R)-N-(1-(Pyridin-4-yl)ethyl)-6-(5-(...)
Affinity DataIC50: 65nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM188075(US9670193, 46 (R)-N-(1-(benzyl(methyl)amino)propan...)
Affinity DataIC50: 66nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187617(US9670193, 28 N-benzyl-5-(5-(trifluoromethyl)-1,2,...)
Affinity DataIC50: 73nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187629(US9670193, 30 N-(pyridin-3-ylmethyl)-5-(5-(trifluo...)
Affinity DataIC50: 79nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187640(US9670193, 33 N-benzyl-3-chloro-5-(5-(trifluoromet...)
Affinity DataIC50: 93nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187224(US9670193, 14 N-methyl-N-(2-(pyridin-4-yl)ethyl)-5...)
Affinity DataIC50: 110nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187217(US9670193, 7 N-(1-phenylethyl)-5-(5-(trifluorometh...)
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187220(US9670193, 10 N-(pyridin-3-ylmethyl)-5-(5-(trifluo...)
Affinity DataIC50: 140nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Novartis

US Patent
LigandPNGBDBM187223(US9670193, 13 (R)-N-(1-phenylpropyl)-5-(5-(trifluo...)
Affinity DataIC50: 140nMAssay Description:Human recombinant full length HDAC6 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187547(US9670193, 22 (R)-N-(1-(diethylamino)-3-methylbuta...)
Affinity DataIC50: 160nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM188027(US9670193, 43 N-(Pyridin-4-ylmethyl)-2-(5-(trifluo...)
Affinity DataIC50: 190nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187993(US9670193, 40 N-benzyl-6-(5-(trifluoromethyl)-1,2,...)
Affinity DataIC50: 200nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Novartis

US Patent
LigandPNGBDBM187232(US9670193, 15 N-(1-(pyridin-4-yl)propyl)-5-(5-(tri...)
Affinity DataIC50: 210nMAssay Description:Human recombinant full length HDAC6 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187221(US9670193, 11 N-((6-methylpyridin-2-yl)methyl)-5-(...)
Affinity DataIC50: 240nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Novartis

US Patent
LigandPNGBDBM187218(US9670193, 8 N-((6-methylpyridin-3-yl)methyl)-5-(5...)
Affinity DataIC50: 250nMAssay Description:Human recombinant full length HDAC6 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187246(US9670193, 18 (R)-N-(1-(dimethylamino)propan-2-yl)...)
Affinity DataIC50: 250nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Novartis

US Patent
LigandPNGBDBM187213(US9670193, 4 N-benzyl-5-(5-(trifluoromethyl)-1,2,4...)
Affinity DataIC50: 320nMAssay Description:Human recombinant full length HDAC6 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Novartis

US Patent
LigandPNGBDBM187222(US9670193, 12 (R)-N-(1-phenylethyl)-5-(5-(trifluor...)
Affinity DataIC50: 340nMAssay Description:Human recombinant full length HDAC6 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Novartis

US Patent
LigandPNGBDBM187242(US9670193, 16 N-(1-(2-methylpyridin-4-yl)ethyl)-5-...)
Affinity DataIC50: 350nMAssay Description:Human recombinant full length HDAC6 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187307(US9670193, 19 N-(1-(dimethylamino)propan-2-yl)-6-(...)
Affinity DataIC50: 350nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Novartis

US Patent
LigandPNGBDBM187217(US9670193, 7 N-(1-phenylethyl)-5-(5-(trifluorometh...)
Affinity DataIC50: 400nMAssay Description:Human recombinant full length HDAC6 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187604(US9670193, 26 (R)-N-(1-(dimethylamino)propan-2-yl)...)
Affinity DataIC50: 420nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 4 [2-1084](Human)
Novartis

US Patent
LigandPNGBDBM187138(US9670193, 1 N-(5-(5-(trifluoromethyl)-1,2,4-oxadi...)
Affinity DataIC50: 460nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Novartis

US Patent
LigandPNGBDBM187221(US9670193, 11 N-((6-methylpyridin-2-yl)methyl)-5-(...)
Affinity DataIC50: 510nMAssay Description:Human recombinant full length HDAC1 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Novartis

US Patent
LigandPNGBDBM187221(US9670193, 11 N-((6-methylpyridin-2-yl)methyl)-5-(...)
Affinity DataIC50: 550nMAssay Description:Human recombinant full length HDAC6 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Novartis

US Patent
LigandPNGBDBM187219(US9670193, 9 N-(1-(pyridin-4-yl)ethyl)-5-(5-(trifl...)
Affinity DataIC50: 560nMAssay Description:Human recombinant full length HDAC6 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent

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