Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 115
LigandPNGBDBM176795(US9675612, 33 {7-[(6-Methoxy-1H-indazol-5-yl)amino...)
Affinity DataIC50: 17nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176749(US9675612, 4 2-Benzyl-N-(6-methoxy-1H-indazol-5-yl...)
Affinity DataIC50: 20nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176754(US9675612, 5 N-(6-Methoxy-1H-indazol-5-yl)-2-(meth...)
Affinity DataIC50: 25nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176814(US9675612, 47 N-[3-(Dimethylamino)-3-oxopropyl]-7-...)
Affinity DataIC50: 32nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176796(US9675612, 34 {7-[(6-Ethoxy-1H-indazol-5-yl)amino]...)
Affinity DataIC50: 34nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176767(US9675612, 11 2-Benzyl-N-(1H-indazol-5-yl)[1,3]thi...)
Affinity DataIC50: 35nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176777(US9675612, 20 2-[(Benzyloxy)methyl]-N-(6-methoxy-1...)
Affinity DataIC50: 36nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176763(US9675612, 9 2-(Cyclopropylmethyl)-N-(1H-indazol-5...)
Affinity DataIC50: 36nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176745(US9675612, 1 6-{[2-(Cyclopropylmethyl)[1,3]thiazol...)
Affinity DataIC50: 37nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176779(US9675612, 22 N-(6-Methoxy-1H-indazol-5-yl)-2-(2-p...)
Affinity DataIC50: 38nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176791(US9675612, 30 7-[(6-Ethoxy-1H-indazol-5-yl)amino]-...)
Affinity DataIC50: 42nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176772(US9675612, 15 N-(6-Methoxy-1H-indazol-5-yl)[1,3]th...)
Affinity DataIC50: 47nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176803(US9675612, 40 N-[3-(Dimethylamino)-3-oxopropyl]-7-...)
Affinity DataIC50: 49nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176780(US9675612, 23 N-(1H-indazol-5-yl)-2-(2-phenylethyl...)
Affinity DataIC50: 51nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176807(US9675612, 44 N,N-Dimethyl-7-{[6-(propan-2-yloxy)-...)
Affinity DataIC50: 52nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176766(US9675612, 10 2-Cyclobutyl-N-(1H-indazol-5-yl)[1,3...)
Affinity DataIC50: 54nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176761(US9675612, 8 2-Cyclohexyl-N-(1H-indazol-5-yl)[1,3]...)
Affinity DataIC50: 56nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176808(US9675612, 45 N-[2-(Dimethylamino)-2-oxoethyl]-7-[...)
Affinity DataIC50: 57nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176799(US9675612, 36 N-[2-(Dimethylamino)-2-oxoethyl]-7-(...)
Affinity DataIC50: 81nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176783(US9675612, 26 4-{7-[(6-Methoxy-1H-indazol-5-yl)ami...)
Affinity DataIC50: 85nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176746(US9675612, 2 6-[(2-Cyclobutyl[1,3]thiazolo[5,4-d]p...)
Affinity DataIC50: 87nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176802(US9675612, 39 N-[2-(Dimethylamino)-2-oxoethyl]-N-m...)
Affinity DataIC50: 98nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176778(US9675612, 21 3-[7-(1H-Indazol-5-ylamino)[1,3]thia...)
Affinity DataIC50: 100nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176798(US9675612, 35 Piperidin-1-yl(7-{[6-(propan-2-yloxy...)
Affinity DataIC50: 102nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176775(US9675612, 18 5-Methoxy-6-([1,3]thiazolo[5,4-d]pyr...)
Affinity DataIC50: 104nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176770(US9675612, 13 4-[7-(1H-Indazol-5-ylamino)[1,3]thia...)
Affinity DataIC50: 122nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176805(US9675612, 42 N-[3-(Dimethylamino)-3-oxopropyl]-7-...)
Affinity DataIC50: 125nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176771(US9675612, 14 1-(3-Hydroxy-3-methylazetidin-1-yl)-...)
Affinity DataIC50: 126nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176801(US9675612, 38 N-[2-(Dimethylamino)-2-oxoethyl]-7-[...)
Affinity DataIC50: 136nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176794(US9675612, 32 6-{[2-(Piperidin-1-ylcarbonyl)[1,3]t...)
Affinity DataIC50: 137nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176776(US9675612, 19 6-([1,3]Thiazolo[5,4-d]pyrimidin-7-y...)
Affinity DataIC50: 159nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176769(US9675612, 12 1-(3-Hydroxy-3-methylazetidin-1-yl)-...)
Affinity DataIC50: 173nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176810(US9675612, 46 N-[3-(Dimethylamino)-3-oxopropyl]-7-...)
Affinity DataIC50: 184nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176773(US9675612, 16 N-(1H-Indazol-5-yl)[1,3]thiazolo[5,4...)
Affinity DataIC50: 186nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176793(US9675612, 31 [7-(1H-Indazol-5-ylamino)[1,3]thiazo...)
Affinity DataIC50: 188nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176747(US9675612, 3 6-[(2-Cyclohexyl[1,3]thiazolo[5,4-d]p...)
Affinity DataIC50: 197nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176790(US9675612, 29 7-[(6-Methoxy-1H-indazol-5-yl)amino]...)
Affinity DataIC50: 199nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176806(US9675612, 43 7-(1H-Indazol-5-ylamino)-N,N-dimethy...)
Affinity DataIC50: 202nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176774(US9675612, 17 2-(2-Phenylethyl)-N-[6-(propan-2-ylo...)
Affinity DataIC50: 229nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176757(US9675612, 7 6-[(2-Cyclohexyl[1,3]thiazolo[5,4-d]p...)
Affinity DataIC50: 354nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176784(US9675612, 27 N,N-Dimethyl-7-[(2-oxo-2,3-dihydro-1...)
Affinity DataIC50: 408nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176800(US9675612, 37 N-[2-(Dimethylamino)-2-oxoethyl]-N-m...)
Affinity DataIC50: 445nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176785(US9675612, 28 7-[(5-Methoxy-2-oxo-2,3-dihydro-1,3-...)
Affinity DataIC50: 1.08E+3nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176804(US9675612, 41 N-[3-(Dimethylamino)-3-oxopropyl]-N-...)
Affinity DataIC50: 2.75E+3nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent

LigandPNGBDBM176782(US9675612, 25 5-Methoxy-6-{[2-(2-phenylethyl)[1,3]...)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent