Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 47
TargetBromodomain-containing protein 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 44nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetBromodomain testis-specific protein(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 147nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106150(US9695172, 3)
Affinity DataIC50: 1.37E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106153(US9695172, 2-227)
Affinity DataIC50: 2.14E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106152(US9695172, 2-221)
Affinity DataIC50: 2.99E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetBromodomain testis-specific protein(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106150(US9695172, 3)
Affinity DataIC50: 3.68E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetBromodomain testis-specific protein(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106153(US9695172, 2-227)
Affinity DataIC50: 5.41E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetBromodomain testis-specific protein(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106152(US9695172, 2-221)
Affinity DataIC50: 5.66E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetAurora kinase C(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106152(US9695172, 2-221)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetAurora kinase B(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106152(US9695172, 2-221)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetAurora kinase A(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106152(US9695172, 2-221)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106153(US9695172, 2-227)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106150(US9695172, 3)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetBromodomain testis-specific protein(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50355500(CHEMBL1908394 | US9695172, GSK461364)
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50355500(CHEMBL1908394 | US9695172, GSK461364)
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent