Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 364
TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM263926(US9714224, 41 | US9714224, 40)
Affinity DataIC50: 10.9nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM263925(US9714224, 34)
Affinity DataIC50: 33.5nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM263928(US9714224, 48)
Affinity DataIC50: 79.5nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM263930(US9714224, 50)
Affinity DataIC50: 96.2nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM263931(US9714224, 51)
Affinity DataIC50: 133nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM263929(US9714224, 49)
Affinity DataIC50: 206nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM263923(US9714221, Example 219N/A*: Not available. Prodrug...)
Affinity DataIC50: 431nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM263926(US9714224, 41 | US9714224, 40)
Affinity DataIC50: 1.79E+3nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs. The binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent