Compile Data Set for Download or QSAR
Report error Found 371 Enz. Inhib. hit(s) with all data for entry = 1573
LigandPNGBDBM331445(US9725449, Example 282)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331447(BDBM331448 | 2-{5-[4-(2H3)Methyl-1-methyl-1H-1,2,3...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331446(US9725449, Example 283 | 5-(Dimethyl-1H-1,2,3-tria...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331447(BDBM331448 | 2-{5-[4-(2H3)Methyl-1-methyl-1H-1,2,3...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331451(US9725449, Example 288 | 11-(Cyclopropylmethoxy)-5...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331195(5-(Dimethyl-1H-1,2,3-triazol-5-yl)-10-fluoro-8-[(S...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331450(US9725449, Example 287 | 11-Methoxy-5-[4-(2H3)meth...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331441(US9725449, Example 278 | 2-{10-Fluoro-5-[4-(2H3)me...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331440(US9725449, Example 277 | 10-Methanesulfonyl-5-[4-(...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331442(US9725449, Example 279 | 13-[(2,2-Difluorocyclopro...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331463(US9725449, Example 300 | 13-Methoxy-5-[4-(2H3)meth...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331207(10-Chloro-5-(dimethyl-1H-1,2,3-triazol-5-yl)-N,N-d...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331462(US9725449, Example 299 | 5-[4-(2H3)Methyl-1-methyl...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331205(US9725449, Example 39 | US9725449, Example 40 | 10...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331465(US9725449, Example 302 | 5-[4-(2H3)Methyl-1-methyl...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331209(10-Chloro-5-(dimethyl-1H-1,2,3-triazol-5-yl)-13-et...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331464(US9725449, Example 301 | 5-[4-(2H3)Methyl-1-methyl...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331211(US9725449, Example 45 | 5-(Dimethyl-1,2-oxazol-4-y...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331452(US9725449, Example 289 | US9725449, Example 290 | ...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331196(5-(Dimethyl-1H-1,2,3-triazol-5-yl)-8-[(S)-(2-fluor...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331199(5-(Dimethyl-1H-1,2,3-triazol-5-yl)-13-methanesulfo...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331454(US9725449, Example 291 | 2-{5-[4-(2H3)Methyl-1-met...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331459(US9725449, Example 296 | 10,13-Dichloro-5-[4-(2H3)...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331458(US9725449, Example 295 | 5-[4-(2H3)Methyl-1-methyl...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331215(US9725449, Example 49 | 5-(Dimethyl-1,2-oxazol-4-y...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331223(5-(Dimethyl-1H-1,2,3-triazol-5-yl)-10-methanesulfo...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331219(5-(Dimethyl-1H-1,2,3-triazol-5-yl)-13-ethoxy-10-me...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331225(US9725449, Example 59 | US9725449, Example 101 | 1...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331223(5-(Dimethyl-1H-1,2,3-triazol-5-yl)-10-methanesulfo...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331227(2-({10-Methanesulfonyl-5-[4-(2H3)methyl-1-methyl-1...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331211(US9725449, Example 45 | 5-(Dimethyl-1,2-oxazol-4-y...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331212(US9725449, Example 46 | 5-(Dimethyl-1H-1,2,3-triaz...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331215(US9725449, Example 49 | 5-(Dimethyl-1,2-oxazol-4-y...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331214(5-(Dimethyl-1,2-oxazol-4-yl)-8-[(S)-(2-fluoropheny...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331216(US9725449, Example 50 | US9725449, Example 51 | 5-...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331216(US9725449, Example 50 | US9725449, Example 51 | 5-...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331219(5-(Dimethyl-1H-1,2,3-triazol-5-yl)-13-ethoxy-10-me...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331218(5-(Dimethyl-1H-1,2,3-triazol-5-yl)-8-[(S)-(4-fluor...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331236(US9725449, Example 71 | 8-[(3-Fluoropyridin-2-yl)(...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331243(13-Ethoxy-8-[(S)-(4-fluorophenyl)(oxan-4-yl)methyl...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331242(13-(Cyclopropylmethoxy)-8-[(S)-(2-fluorophenyl)(ox...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331229(2-({8-[(S)-(2-Fluorophenyl)(oxan-4-yl)methyl]-10-m...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331228(13-Ethoxy-8-[(S)-(2-fluorophenyl)(oxan-4-yl)methyl...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331230(US9725449, Example 64 | 8-[(3-Fluoropyridin-2-yl)(...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331234(13-Ethoxy-8-[(3-fluoropyridin-2-yl)(oxan-4-yl)meth...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331509(2-{5-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331501(US9725449, Example 341 | 8-[(S)-(3-Fluoropyridin-2...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331245(8-[(S)-(4-Fluorophenyl)(oxan-4-yl)methyl]-10-metha...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331244(13-(Cyclopropylmethoxy)-8-[(S)-(4-fluorophenyl)(ox...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

LigandPNGBDBM331503(US9725449, Example 343 | 11-(4,4-Difluoropiperidin...)
Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

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