Compile Data Set for Download or QSAR
Report error Found 100 Enz. Inhib. hit(s) with all data for entry = 1711
TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336520BDBM336520(1-(7-fluoro-5-(4- methylpyridin-3- yl)indolin-1-yl...)
Affinity DataIC50: 0.200nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019871BDBM50019871(CHEMBL3287192 | US9745282, 51)
Affinity DataIC50: 0.600nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336320BDBM336320(1-(7-chloro-5- (isoquinolin-4-yl) indolin-1- yl)et...)
Affinity DataIC50: 0.700nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019886BDBM50019886(CHEMBL3287178 | US9745282, 28)
Affinity DataIC50: 0.700nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336516BDBM336516((R)-1-(7-fluoro-5-(5- (1,1,1-trifluoro-2- hydroxyp...)
Affinity DataIC50: 0.800nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336351BDBM336351(1-(7-fluoro-5-(5- fluoro-4- methylpyridine-3- yl)i...)
Affinity DataIC50: 1nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336322BDBM336322(US9745282, 5 | (S)-1-(7-chloro-5-(5- (1,1,1,-trifl...)
Affinity DataIC50: 1.20nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336331BDBM336331(1-(7-chloro-5-(5- fluoro-4- methylpyridin-3- yl)in...)
Affinity DataIC50: 1.40nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336515BDBM336515(1-(5-(4-ethyl-5- fluoropyridine-3-yl)- 7-fluoroind...)
Affinity DataIC50: 1.60nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336516BDBM336516((R)-1-(7-fluoro-5-(5- (1,1,1-trifluoro-2- hydroxyp...)
Affinity DataIC50: 2.10nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019867BDBM50019867(CHEMBL3287188 | US9745282, 58)
Affinity DataIC50: 2.20nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336330BDBM336330(1-(7-chloro-5-(4- ethyl-5- fluoropyridin-3- yl)ind...)
Affinity DataIC50: 2.30nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336322BDBM336322(US9745282, 5 | (S)-1-(7-chloro-5-(5- (1,1,1,-trifl...)
Affinity DataIC50: 2.40nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019887BDBM50019887(CHEMBL3287179 | US9745282, 29)
Affinity DataIC50: 2.80nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019895BDBM50019895(CHEMBL3287187 | US9745282, 57)
Affinity DataIC50: 3nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336267BDBM336267(1-(7-chloro-5-(5- methoxypyridin-3- yl)indolin-1- ...)
Affinity DataIC50: 4.10nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336332BDBM336332(1-(7-fluoro-5- (pyridine-3-yl) indolin-1-yl) ethan...)
Affinity DataIC50: 4.90nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336313BDBM336313(1-(7-chloro-5-(4- (trifluoromethyl)pyri dine-3-yl)...)
Affinity DataIC50: 5nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336542BDBM336542(1-(5-(pyridin-3- yl)indolin-1- yl)ethanethione | U...)
Affinity DataIC50: 6nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336235BDBM336235(1-(7-chloro-5-(pyridin-3-yl)indolin-1-yl)ethanone ...)
Affinity DataIC50: 7.40nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336321BDBM336321(1-(7-chloro-5-(5- (triuoromethyl)pyri dine-3-yl)in...)
Affinity DataIC50: 7.5nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336540BDBM336540(1-(7-chloro-5-(5- fluoropyridin-3- yl)indon-1-yl)-...)
Affinity DataIC50: 10.6nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336519BDBM336519(5-(1-acetyl-7- fluoroindolin-5-yl)- 4-methylnicoti...)
Affinity DataIC50: 12nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336244BDBM336244(1-(7-chloro-5-(5- fluoropyridine- 3-yl)indolin-1- ...)
Affinity DataIC50: 12nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336516BDBM336516((R)-1-(7-fluoro-5-(5- (1,1,1-trifluoro-2- hydroxyp...)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336347BDBM336347(1-(7-fluoro-5-(5- fluoropyridine-3- yl)indolin-1-y...)
Affinity DataIC50: 15nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019893BDBM50019893(CHEMBL3287185 | US9745282, 54)
Affinity DataIC50: 16nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336541BDBM336541(2,2,2-trifluoro-1-(7- fluoro-5-(5- fluoropyridin-3...)
Affinity DataIC50: 17.4nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336516BDBM336516((R)-1-(7-fluoro-5-(5- (1,1,1-trifluoro-2- hydroxyp...)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019869BDBM50019869(CHEMBL3287190 | US9745282, 50)
Affinity DataIC50: 23nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336322BDBM336322(US9745282, 5 | (S)-1-(7-chloro-5-(5- (1,1,1,-trifl...)
Affinity DataIC50: 26nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019889BDBM50019889(CHEMBL3287181 | US9745282, 30)
Affinity DataIC50: 30nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019871BDBM50019871(CHEMBL3287192 | US9745282, 51)
Affinity DataIC50: 34nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336317BDBM336317(5-(1-acetyl-7- chloroindolin-5-yl) 4- methylnicoti...)
Affinity DataIC50: 35nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019892BDBM50019892(CHEMBL3287184 | US9745282, 55)
Affinity DataIC50: 36nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336347BDBM336347(1-(7-fluoro-5-(5- fluoropyridine-3- yl)indolin-1-y...)
Affinity DataIC50: 50.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019886BDBM50019886(CHEMBL3287178 | US9745282, 28)
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336322BDBM336322(US9745282, 5 | (S)-1-(7-chloro-5-(5- (1,1,1,-trifl...)
Affinity DataIC50: 53nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019894BDBM50019894(CHEMBL3287186 | US9745282, 56)
Affinity DataIC50: 55nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336320BDBM336320(1-(7-chloro-5- (isoquinolin-4-yl) indolin-1- yl)et...)
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019891BDBM50019891(CHEMBL3287183 | US9745282, 52)
Affinity DataIC50: 61nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336520BDBM336520(1-(7-fluoro-5-(4- methylpyridin-3- yl)indolin-1-yl...)
Affinity DataIC50: 68nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336518BDBM336518(5-(1-acetyl-7- fluoroindolin-5- yl)nicotinonitrile...)
Affinity DataIC50: 97nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336351BDBM336351(1-(7-fluoro-5-(5- fluoro-4- methylpyridine-3- yl)i...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019891BDBM50019891(CHEMBL3287183 | US9745282, 52)
Affinity DataIC50: 110nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336267BDBM336267(1-(7-chloro-5-(5- methoxypyridin-3- yl)indolin-1- ...)
Affinity DataIC50: 130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019888BDBM50019888(CHEMBL3287180 | US9745282, 31)
Affinity DataIC50: 152nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 50019895BDBM50019895(CHEMBL3287187 | US9745282, 57)
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336523BDBM336523(1-(5-(4-ethyl-5- fluoropyridin-3-yl)- 6-fluoroindo...)
Affinity DataIC50: 170nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 336521BDBM336521(1-(6-fluoro-5- (pyridin-3- yl)indon-1- yl)ethanone...)
Affinity DataIC50: 180nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

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