Compile Data Set for Download or QSAR
Report error Found 159 Enz. Inhib. hit(s) with all data for entry = 1823
TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM8366(CHEMBL1809169 | US8822448, 147 | US9771375, Exampl...)
Affinity DataIC50: 30nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM8526(CHEMBL1809170 | US8822447, 107 | US8822448, 184 | ...)
Affinity DataIC50: 40nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130666(US8822447, 180 | US9771375, Example 180)
Affinity DataIC50: 40nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349744(CHEMBL1809171 | US8822447, 140 | US9771375, Exampl...)
Affinity DataIC50: 90nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM342484(US9771375, Example 66 | N-(3-methyl-1-phenyl-1H-in...)
Affinity DataIC50: 160nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349746(CHEMBL1809173 | US8822447, 116 | US9771375, Exampl...)
Affinity DataIC50: 160nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349732(CHEMBL1809159 | US8822447, 2 | US9771375, Example ...)
Affinity DataIC50: 220nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130643(US8822447, 153 | US8822447, 141 | US9771375, Examp...)
Affinity DataIC50: 230nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349741(CHEMBL1809168 | US8822447, 139 | US9771375, Exampl...)
Affinity DataIC50: 230nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130550(US8822447, 14 | US9771375, Example 14)
Affinity DataIC50: 230nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130549(US8822447, 13 | US9771375, Example 13)
Affinity DataIC50: 260nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130618(US8822447, 98 | US9771375, Example 98)
Affinity DataIC50: 300nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130564(US8822447, 29 | US9771375, Example 29)
Affinity DataIC50: 300nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130651(US8822447, 157 | US9771375, Example 157)
Affinity DataIC50: 300nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130597(US8822447, 75 | US9771375, Example 75)
Affinity DataIC50: 310nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349730(CHEMBL1809157 | US8822447, 12 | US9771375, Example...)
Affinity DataIC50: 310nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM8368(CHEMBL1809167 | US8822447, 106 | US8822448, 179 | ...)
Affinity DataIC50: 360nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130632(US8822447, 119 | US9771375, Example 119)
Affinity DataIC50: 380nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349734(CHEMBL1809161 | US8822447, 132 | US9771375, Exampl...)
Affinity DataIC50: 380nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM342491(US9771375, Example 73 | 3-Methoxy-1-phenyl-6-(3-(p...)
Affinity DataIC50: 390nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130593(US8822447, 71 | US9771375, Example 71)
Affinity DataIC50: 400nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130643(US8822447, 153 | US8822447, 141 | US9771375, Examp...)
Affinity DataIC50: 400nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130629(US8822447, 112 | US9771375, Example 112)
Affinity DataIC50: 420nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130569(US8822447, 35 | US9771375, Example 35)
Affinity DataIC50: 430nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM8526(CHEMBL1809170 | US8822447, 107 | US8822448, 184 | ...)
Affinity DataIC50: 440nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130544(US8822447, 4 | US9771375, Example 4)
Affinity DataIC50: 450nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130560(US8822447, 25 | US9771375, Example 25)
Affinity DataIC50: 460nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130646(US8822447, 149 | US9771375, Example 149)
Affinity DataIC50: 480nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349745(CHEMBL1809172 | US8822447, 124 | US9771375, Exampl...)
Affinity DataIC50: 490nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130548(US8822447, 11 | US9771375, Example 11)
Affinity DataIC50: 540nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349724(CHEMBL1809151 | US8822447, 1 | US9771375, Example ...)
Affinity DataIC50: 560nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130551(US8822447, 15 | US9771375, Example 15)
Affinity DataIC50: 560nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130555(US8822447, 19 | US9771375, Example 19)
Affinity DataIC50: 560nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349751(CHEMBL1809178 | US8822447, 46 | US9771375, Example...)
Affinity DataIC50: 560nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349750(CHEMBL1809177 | US8822447, 42 | US9771375, Example...)
Affinity DataIC50: 570nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349731(CHEMBL1809158 | US8822447, 5 | US9771375, Example ...)
Affinity DataIC50: 590nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50330259(N-[3-(methylsulfanyl)-1-phenyl-1H-indazol-6-yl]pip...)
Affinity DataIC50: 590nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130619(US8822447, 99 | US9771375, Example 99)
Affinity DataIC50: 600nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130657(US8822447, 166 | US9771375, Example 166)
Affinity DataIC50: 600nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130663(US8822447, 175 | US9771375, Example 175)
Affinity DataIC50: 610nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130623(US8822447, 103 | US9771375, Example 103)
Affinity DataIC50: 660nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130658(US8822447, 167 | US9771375, Example 167)
Affinity DataIC50: 660nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130644(US8822447, 142 | US9771375, Example 142)
Affinity DataIC50: 670nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130556(US8822447, 20 | US9771375, Example 20)
Affinity DataIC50: 670nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130638(US8822447, 131 | US9771375, Example 131)
Affinity DataIC50: 680nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349735(CHEMBL1809162 | US8822447, 23 | US9771375, Example...)
Affinity DataIC50: 680nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50349759(CHEMBL1809186 | US8822447, 40 | US9771375, Example...)
Affinity DataIC50: 680nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130594(US8822447, 72 | US9771375, Example 72)
Affinity DataIC50: 680nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130545(US8822447, 7 | US9771375, Example 7)
Affinity DataIC50: 700nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetKetohexokinase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130652(US8822447, 158 | US9771375, Example 158)
Affinity DataIC50: 700nMAssay Description:An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

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