Compile Data Set for Download or QSAR
Report error Found 211 Enz. Inhib. hit(s) with all data for entry = 1837
TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342631BDBM342631(5-[4-((R)-2-Hydroxy-propionyl)-piperazin-1-ylmethy...)
Affinity DataIC50: 0.122nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342634BDBM342634(5-[4-(Pyridine-3-carbonyl)-piperazin-1-ylmethyl]-t...)
Affinity DataIC50: 0.168nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342633BDBM342633(5-{4-[2-(2-Chloro-phenyl)-acetyl]-piperazin-1-ylme...)
Affinity DataIC50: 0.407nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342635BDBM342635(5-[4-((1R,2R)-2-Phenyl-cyclopropane-carbonyl)-pipe...)
Affinity DataIC50: 0.432nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342632BDBM342632(5-[4-(3,5-Dimethyl-isoxazole-4-carbonyl)-piperazin...)
Affinity DataIC50: 0.502nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342638BDBM342638(5-[4-(Pyrazolo[1,5-a]pyridine-3-carbonyl)-piperazi...)
Affinity DataIC50: 0.512nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342637BDBM342637(5-[4-(2-Methoxy-pyridine-3-carbonyl)-piperazin-1-y...)
Affinity DataIC50: 0.524nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342636BDBM342636(5-[4-(Bicyclo[4.2.0]octa-1(6),2,4-triene-7-carbony...)
Affinity DataIC50: 0.528nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342646BDBM342646(5-[4-(Pyridine-2-carbonyl)-piperazin-1-ylmethyl]-t...)
Affinity DataIC50: 0.534nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342650BDBM342650(5-[4-(2-Hydroxy-propionyl)-piperazin-1-ylmethyl]-t...)
Affinity DataIC50: 0.539nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342645BDBM342645(5-[4-(Imidazo[1,2-a]pyridine-6-carbonyl)-piperazin...)
Affinity DataIC50: 0.604nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342648BDBM342648(5-[4-(4-Bromo-thiophene-3-carbonyl)-piperazin-1-yl...)
Affinity DataIC50: 0.678nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342649BDBM342649(5-[4-(Pyrrolidine-1-carbonyl)-piperazin-1-ylmethyl...)
Affinity DataIC50: 0.695nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342647BDBM342647(5-[4-(2-Phenoxy-acetyl)-piperazin-1-ylmethyl]-thio...)
Affinity DataIC50: 0.699nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342662BDBM342662(5-[4-(2-Hydroxy-propionyl)-piperazin-1-ylmethyl]-t...)
Affinity DataIC50: 0.756nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342661BDBM342661(5-{4-[2-(3-Trifluoromethyl-phenyl)-acetyl]-piperaz...)
Affinity DataIC50: 0.758nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342658BDBM342658(US9776991, Example 159 | 5-[4-(2,4-Dimethyl-6-oxo-...)
Affinity DataIC50: 0.800nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342660BDBM342660(US9776991, Example 30)
Affinity DataIC50: 0.803nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342668BDBM342668(5-(4-Cyclopentyl-3-oxo-piperazin-1-ylmethyl)-thiop...)
Affinity DataIC50: 0.803nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342658BDBM342658(US9776991, Example 159 | 5-[4-(2,4-Dimethyl-6-oxo-...)
Affinity DataIC50: 0.803nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342659BDBM342659(5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-pipe...)
Affinity DataIC50: 0.803nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342657BDBM342657(5-(4-Cyclobutyl-piperazin-1-ylmethyl)-thiophene-2-...)
Affinity DataIC50: 0.803nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342663BDBM342663(5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-pipe...)
Affinity DataIC50: 0.906nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342666BDBM342666(US9776991, Example 46 | 5-[4-(2,4-Dimethyl-6-oxo-6...)
Affinity DataIC50: 0.906nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342666BDBM342666(US9776991, Example 46 | 5-[4-(2,4-Dimethyl-6-oxo-6...)
Affinity DataIC50: 0.906nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342664BDBM342664(5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-pipe...)
Affinity DataIC50: 0.906nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342665BDBM342665(5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-pipe...)
Affinity DataIC50: 0.916nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342667BDBM342667(5-[4-(1-Hydroxy-cyclopropanecarbonyl)-piperazin-1-...)
Affinity DataIC50: 0.929nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342682BDBM342682(5-[4-(4-Bromo-2-methyl-2H-pyrazole-3-carbonyl)-pip...)
Affinity DataIC50: 0.955nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342684BDBM342684(US9776991, Example 155 | US9776991, Example 54)
Affinity DataIC50: 0.976nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342681BDBM342681(5-[4-(1-Methyl-1H-pyrrole-2-carbonyl)-piperazin-1-...)
Affinity DataIC50: 0.994nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342686BDBM342686(5-[3-Oxo-4-(2,2,2-trifluoro-ethyl)-piperazin-1-ylm...)
Affinity DataIC50: 1.01nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342683BDBM342683(5-[4-(2-Ethoxy-benzoyl)-piperazin-1-ylmethyl]-thio...)
Affinity DataIC50: 1.02nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342685BDBM342685(5-[4-(Tetrahydro-furan-3-carbonyl)-piperazin-1-ylm...)
Affinity DataIC50: 1.05nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342690BDBM342690(US9776991, Example 60)
Affinity DataIC50: 1.10nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342687BDBM342687(5-[4-(2-Methoxy-pyridine-3-carbonyl)-piperazin-1-y...)
Affinity DataIC50: 1.13nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342692BDBM342692(5-(2,2-Dimethyl-3-oxo-piperazin-1-ylmethyl)-thioph...)
Affinity DataIC50: 1.14nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342689BDBM342689(5-[4-(2,4-Dimethyl-6-oxo-6H-pyran-3-carbonyl)-pipe...)
Affinity DataIC50: 1.15nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342688BDBM342688(5-[4-(1-Phenyl-cyclopropanecarbonyl)-piperazin-1-y...)
Affinity DataIC50: 1.17nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342691BDBM342691(5-[4-(2-Hydroxy-propionyl)-piperazin-1-ylmethyl]-t...)
Affinity DataIC50: 1.18nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342695BDBM342695(5-[4-(Isoquinoline-1-carbonyl)-piperazin-1-ylmethy...)
Affinity DataIC50: 1.19nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342698BDBM342698(5-[4-(1-Methoxymethyl-cyclopropanecarbonyl)-pipera...)
Affinity DataIC50: 1.19nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342693BDBM342693(5-[4-(2-Phenyl-propionyl)-piperazin-1-ylmethyl]-th...)
Affinity DataIC50: 1.21nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342697BDBM342697(5-[4-(3,6-Dimethoxy-pyridine-2-carbonyl)-piperazin...)
Affinity DataIC50: 1.21nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342694BDBM342694(5-[4-(2-Chloro-4-fluoro-benzoyl)-piperazin-1-ylmet...)
Affinity DataIC50: 1.25nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342696BDBM342696(5-[4-(2-Oxo-1,2-dihydro-pyridine-3-carbonyl)-piper...)
Affinity DataIC50: 1.25nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342723BDBM342723(5-[4-((R)-2-Methoxy-propionyl)-piperazin-1-ylmethy...)
Affinity DataIC50: 1.31nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342722BDBM342722(5-[4-(3-Hydroxy-butyryl)-piperazin-1-ylmethyl]-thi...)
Affinity DataIC50: 1.39nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342719BDBM342719(5-[4-(Pyridine-3-carbonyl)-piperazin-1-ylmethyl]-t...)
Affinity DataIC50: 1.40nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 342790BDBM342790(2-[4-(3,5-Dimethyl-isoxazole-4-carbonyl)-piperazin...)
Affinity DataIC50: 1.41nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

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