Compile Data Set for Download or QSAR
Report error Found 196 Enz. Inhib. hit(s) with all data for entry = 1849
TargetTyrosine-protein kinase JAK1(Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344041BDBM344041(US9777017, Example 25 | US9908895, Example 25 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344100BDBM344100(US9777017, Example 84 | US9908895, Example 84 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344099BDBM344099(US9777017, Example 83 | US9908895, Example 83 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344043BDBM344043(US9777017, Example 27 | US9908895, Example 27 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344102BDBM344102(US9777017, Example 86 | US9908895, Example 86 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344042BDBM344042(US9777017, Example 26 | US9908895, Example 26 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344101BDBM344101(US9777017, Example 85 | US9908895, Example 85 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344096BDBM344096(US9777017, Example 80 | US9908895, Example 80 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344095BDBM344095(US9777017, Example 79 | US9908895, Example 79 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344040BDBM344040(US9777017, Example 24 | US9908895, Example 24 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344098BDBM344098(US9777017, Example 82 | US9908895, Example 82 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344039BDBM344039(US9777017, Example 23 | US10370387, Example 23 | U...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344097BDBM344097(US9777017, Example 81 | US9908895, Example 81 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344048BDBM344048(US9777017, Example 32 | US9908895, Example 32 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344107BDBM344107(US9777017, Example 91 | US9908895, Example 91 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344049BDBM344049(US9777017, Example 33 | US9908895, Example 33 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344104BDBM344104(US9777017, Example 88 | US9908895, Example 88 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344103BDBM344103(US9777017, Example 87 | US9908895, Example 87 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344106BDBM344106(US9777017, Example 90 | US9908895, Example 90 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344105BDBM344105(US9777017, Example 89 | US9908895, Example 89 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344054BDBM344054(US9777017, Example 38 | US9908895, Example 38 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344054BDBM344054(US9777017, Example 38 | US9908895, Example 38 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344053BDBM344053(US9777017, Example 37 | US9908895, Example 37 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344056BDBM344056(US9777017, Example 40 | US11161855, Example 40 (se...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344055BDBM344055(US9777017, Example 39 | US9908895, Example 39 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344052BDBM344052(US9777017, Example 36 | US9908895, Example 36 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344051BDBM344051(US9777017, Example 35 | US9908895, Example 35 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344052BDBM344052(US9777017, Example 36 | US9908895, Example 36 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344059BDBM344059(US9777017, Example 43 | US9908895, Example 43 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Incyte Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 344062BDBM344062(US9777017, Example 46 | US9908895, Example 46)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344061BDBM344061(US9777017, Example 45 | US9908895, Example 45 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344057BDBM344057(US9777017, Example 41 | US11161855, Example 41 (se...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344058BDBM344058(US9777017, Example 42 | US9908895, Example 42 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344064BDBM344064(US9777017, Example 48 | US9908895, Example 48 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344064BDBM344064(US9777017, Example 48 | US9908895, Example 48 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344063BDBM344063(US9777017, Example 47 | US9908895, Example 47 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344018BDBM344018(US9777017, Example 10 | US9777017, Example 2 | US9...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344021BDBM344021(US9777017, Example 5 | US9908895, Example 5 | US10...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344020BDBM344020(US9777017, Example 4 | US9908895, Example 4 | US10...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344074BDBM344074(US9777017, Example 58 | US9908895, Example 58 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344073BDBM344073(US9777017, Example 57 | US9908895, Example 57 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344084BDBM344084(US9777017, Example 68 | US10370387, Example 68 | U...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 344018BDBM344018(US9777017, Example 10 | US9777017, Example 2 | US9...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344028BDBM344028(US9777017, Example 12 | US9908895, Example 12 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344027BDBM344027(US9777017, Example 11 | US9908895, Example 11 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344080BDBM344080(US9777017, Example 64 | US9908895, Example 64 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344023BDBM344023(US9777017, Example 7 | US9908895, Example 7 | US10...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344024BDBM344024(US9777017, Example 8 | US9908895, Example 8 | US10...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344092BDBM344092(US9777017, Example 76 | US9908895, Example 76 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
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LigandChemical structure of BindingDB Monomer ID 344034BDBM344034(US9777017, Example 18 | US9908895, Example 18 | US...)
Affinity DataIC50: 100nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

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