Compile Data Set for Download or QSAR
Report error Found 68 Enz. Inhib. hit(s) with all data for entry = 1867
TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345133BDBM345133(1-(3-(tert-Butyldimethylsilyl)-1-(p-tolyl)-1H-pyra...)
Affinity DataIC50: 5nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345134BDBM345134(1-(4-((2-((3-(2-Morpholinoethoxy)phenyl)amino)pyri...)
Affinity DataIC50: 7nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345134BDBM345134(1-(4-((2-((3-(2-Morpholinoethoxy)phenyl)amino)pyri...)
Affinity DataIC50: 10nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345140BDBM345140(3-Methoxy-N-(2-morpholinoethyl)-5-((4-((4-(3-(1-(p...)
Affinity DataIC50: 10nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345143BDBM345143(1-(4-((2-((7-Methyl-1H-indazol-5-yl)amino)pyrimidi...)
Affinity DataIC50: 15nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345140BDBM345140(3-Methoxy-N-(2-morpholinoethyl)-5-((4-((4-(3-(1-(p...)
Affinity DataIC50: 17nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345149BDBM345149(1-(4-((2-((3-Methoxy-5-(2-(2-(2-methoxyethoxyl)eth...)
Affinity DataIC50: 17nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 345138BDBM345138(1-(4-((2-((2-Oxoindolin-6-yl)amino)pyrimidin-4-yl)...)
Affinity DataIC50: 19nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 345143BDBM345143(1-(4-((2-((7-Methyl-1H-indazol-5-yl)amino)pyrimidi...)
Affinity DataIC50: 24nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 345150BDBM345150(3-Ethynyl-N-(2-morpholinoethyl)-5-((4-((4-(3-(1-(p...)
Affinity DataIC50: 25nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 345136BDBM345136(1-(4-((2-((3-Aminobenzo[d]isoxazol-5-yl)amino)pyri...)
Affinity DataIC50: 37nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345146BDBM345146(1-(2,3-Dichloro-4-((2-((3-methoxy-5-(2-morpholinoe...)
Affinity DataIC50: 41nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345135BDBM345135(1-[4-[2-(1H-Indazol-5-ylamino)pyrimidin-4-yl]oxy-1...)
Affinity DataIC50: 45nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345146BDBM345146(1-(2,3-Dichloro-4-((2-((3-methoxy-5-(2-morpholinoe...)
Affinity DataIC50: 59nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345150BDBM345150(3-Ethynyl-N-(2-morpholinoethyl)-5-((4-((4-(3-(1-(p...)
Affinity DataIC50: 65nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345120BDBM345120(1-(4-((2-(Phenylamino)pyrimidin-4-yl)oxy)naphthale...)
Affinity DataIC50: 77nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345136BDBM345136(1-(4-((2-((3-Aminobenzo[d]isoxazol-5-yl)amino)pyri...)
Affinity DataIC50: 77.5nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 345149BDBM345149(1-(4-((2-((3-Methoxy-5-(2-(2-(2-methoxyethoxyl)eth...)
Affinity DataIC50: 89nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 345130BDBM345130(1-(1-(6-Methoxypyridin-3-yl)-3-(trimethylsilyl)-1H...)
Affinity DataIC50: 93nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 345141BDBM345141(1-(4-((2-((3-Methoxy-5-(2-morpholinoethoxy)phenyl)...)
Affinity DataIC50: 106nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345150BDBM345150(3-Ethynyl-N-(2-morpholinoethyl)-5-((4-((4-(3-(1-(p...)
Affinity DataIC50: 108nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 345144BDBM345144(1-(3-(Ethyldimethylsilyl)-1-(p-tolyl)-1H-pyrazol-5...)
Affinity DataIC50: 116nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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LigandChemical structure of BindingDB Monomer ID 345130BDBM345130(1-(1-(6-Methoxypyridin-3-yl)-3-(trimethylsilyl)-1H...)
Affinity DataIC50: 120nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandChemical structure of BindingDB Monomer ID 345137BDBM345137(1-(4-((2-((7-Methyl-1H-indazol-5-yl)amino)pyrimidi...)
Affinity DataIC50: 135nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
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LigandChemical structure of BindingDB Monomer ID 345140BDBM345140(3-Methoxy-N-(2-morpholinoethyl)-5-((4-((4-(3-(1-(p...)
Affinity DataIC50: 142nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
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LigandChemical structure of BindingDB Monomer ID 345120BDBM345120(1-(4-((2-(Phenylamino)pyrimidin-4-yl)oxy)naphthale...)
Affinity DataIC50: 152nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345141BDBM345141(1-(4-((2-((3-Methoxy-5-(2-morpholinoethoxy)phenyl)...)
Affinity DataIC50: 170nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345149BDBM345149(1-(4-((2-((3-Methoxy-5-(2-(2-(2-methoxyethoxyl)eth...)
Affinity DataIC50: 204nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345131BDBM345131(1-(1-(4-(2-Morpholinoethoxy)phenyl)-3-(trimethylsi...)
Affinity DataIC50: 227nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345143BDBM345143(1-(4-((2-((7-Methyl-1H-indazol-5-yl)amino)pyrimidi...)
Affinity DataIC50: 244nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
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LigandChemical structure of BindingDB Monomer ID 345143BDBM345143(1-(4-((2-((7-Methyl-1H-indazol-5-yl)amino)pyrimidi...)
Affinity DataIC50: 253nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 345136BDBM345136(1-(4-((2-((3-Aminobenzo[d]isoxazol-5-yl)amino)pyri...)
Affinity DataIC50: 269nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
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LigandChemical structure of BindingDB Monomer ID 345134BDBM345134(1-(4-((2-((3-(2-Morpholinoethoxy)phenyl)amino)pyri...)
Affinity DataIC50: 314nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345149BDBM345149(1-(4-((2-((3-Methoxy-5-(2-(2-(2-methoxyethoxyl)eth...)
Affinity DataIC50: 320nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345141BDBM345141(1-(4-((2-((3-Methoxy-5-(2-morpholinoethoxy)phenyl)...)
Affinity DataIC50: 320nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
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LigandChemical structure of BindingDB Monomer ID 345130BDBM345130(1-(1-(6-Methoxypyridin-3-yl)-3-(trimethylsilyl)-1H...)
Affinity DataIC50: 329nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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LigandChemical structure of BindingDB Monomer ID 345148BDBM345148(1-(4-((2-((1-Oxoisoindolin-5-yl)amino)pyrimidin-4-...)
Affinity DataIC50: 345nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
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LigandChemical structure of BindingDB Monomer ID 345131BDBM345131(1-(1-(4-(2-Morpholinoethoxy)phenyl)-3-(trimethylsi...)
Affinity DataIC50: 347nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
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LigandChemical structure of BindingDB Monomer ID 345137BDBM345137(1-(4-((2-((7-Methyl-1H-indazol-5-yl)amino)pyrimidi...)
Affinity DataIC50: 358nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345142BDBM345142(1-(4-((2-(pyridin-2-ylamino)pyrimidin-4-yl)oxy)nap...)
Affinity DataIC50: 360nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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LigandChemical structure of BindingDB Monomer ID 345147BDBM345147(3-Methoxy-N-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyh...)
Affinity DataIC50: 370nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345135BDBM345135(1-[4-[2-(1H-Indazol-5-ylamino)pyrimidin-4-yl]oxy-1...)
Affinity DataIC50: 380nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345150BDBM345150(3-Ethynyl-N-(2-morpholinoethyl)-5-((4-((4-(3-(1-(p...)
Affinity DataIC50: 416nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345140BDBM345140(3-Methoxy-N-(2-morpholinoethyl)-5-((4-((4-(3-(1-(p...)
Affinity DataIC50: 461nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345131BDBM345131(1-(1-(4-(2-Morpholinoethoxy)phenyl)-3-(trimethylsi...)
Affinity DataIC50: 498nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 345137BDBM345137(1-(4-((2-((7-Methyl-1H-indazol-5-yl)amino)pyrimidi...)
Affinity DataIC50: 520nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345138BDBM345138(1-(4-((2-((2-Oxoindolin-6-yl)amino)pyrimidin-4-yl)...)
Affinity DataIC50: 541nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 345135BDBM345135(1-[4-[2-(1H-Indazol-5-ylamino)pyrimidin-4-yl]oxy-1...)
Affinity DataIC50: 673nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 345139BDBM345139(1-(4-((2-((3-(2-(Dimethylamino)ethoxy)phenyl)amino...)
Affinity DataIC50: 690nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
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LigandChemical structure of BindingDB Monomer ID 345138BDBM345138(1-(4-((2-((2-Oxoindolin-6-yl)amino)pyrimidin-4-yl)...)
Affinity DataIC50: 990nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

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