Compile Data Set for Download or QSAR
Report error Found 119 Enz. Inhib. hit(s) with all data for entry = 1945
TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347545BDBM347545(4-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...)
Affinity DataIC50: 30nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347538BDBM347538(4-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...)
Affinity DataIC50: 30nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347585BDBM347585(5-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...)
Affinity DataIC50: 30nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347577BDBM347577(4-{[3-(4-Methoxy-2-methylphenyl)piperidin-1-yl]car...)
Affinity DataIC50: 40nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347578BDBM347578(4-({3-[4-Methoxy-2-(trifluoromethyl)phenyl]piperid...)
Affinity DataIC50: 50nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347571BDBM347571(4-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...)
Affinity DataIC50: 50nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347579BDBM347579(4-{[3-(4-Chloro-2-ethoxyphenyl)piperidin-1-yl]carb...)
Affinity DataIC50: 70nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347518BDBM347518(3-Chloro-5-{[3-(4-chloro-2-methylphenyl)piperidin-...)
Affinity DataIC50: 70nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347585BDBM347585(5-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...)
Affinity DataIC50: 70nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347591BDBM347591(5-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...)
Affinity DataIC50: 80nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347547BDBM347547(2-(Azetidin-1-yl)-4-{[3-(4-chloro-2-methylphenyl)p...)
Affinity DataIC50: 90nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347599BDBM347599(5-{[3-(4-Chloro-2-ethoxyphenyl)piperidin-1-yl]carb...)
Affinity DataIC50: 90nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347575BDBM347575(4-{[3-(4-Chloro-2-ethoxyphenyl)piperidin-1-yl]carb...)
Affinity DataIC50: 100nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347576BDBM347576(4-({3-[4-Methoxy-2-(trifluoromethyl)phenyl]piperid...)
Affinity DataIC50: 100nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347612BDBM347612(3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-[(1-methy...)
Affinity DataIC50: 100nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347521BDBM347521(3-Chloro-5-{[3-(4-methoxy-2-methylphenyl)piperidin...)
Affinity DataIC50: 100nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347590BDBM347590(5-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...)
Affinity DataIC50: 110nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347607BDBM347607(3-(4-Chloro-2-methylphenyl)-1-[(1-ethyl-1H-pyrazol...)
Affinity DataIC50: 110nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347584BDBM347584(5-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...)
Affinity DataIC50: 120nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347541BDBM347541(4-{[3-(4-Chlorophenyl)piperidin-1-yl]carbonyl}-N-m...)
Affinity DataIC50: 130nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347596BDBM347596(5-({3-[4-Methoxy-2-(trifluoromethyl)phenyl]piperid...)
Affinity DataIC50: 130nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347594BDBM347594(5-{[3-(4-Methoxy-2-methylphenyl)piperidin-1-yl]car...)
Affinity DataIC50: 130nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347610BDBM347610(4-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...)
Affinity DataIC50: 150nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347595BDBM347595(5-{[3-(4-Methoxy-2-methylphenyl)piperidin-1-yl]car...)
Affinity DataIC50: 160nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347609BDBM347609(3-(4-Chloro-2-methylphenyl)-1-[(1-methyl-1H-pyrazo...)
Affinity DataIC50: 170nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347613BDBM347613(3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-[(1-ethyl...)
Affinity DataIC50: 170nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347598BDBM347598(5-{[3-(4-Chloro-2-ethoxyphenyl)piperidin-1-yl]carb...)
Affinity DataIC50: 170nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347608BDBM347608(3-(4-Chloro-2-methylphenyl)-1-{[1-(propan-2-yl)-1H...)
Affinity DataIC50: 180nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347532BDBM347532(4-{[(3R)-3-(4-Chlorophenyl)piperidin-1-yl]carbonyl...)
Affinity DataIC50: 180nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347528BDBM347528(N,N-Dimethyl-4-{[3-(2-methylphenyl)piperidin-1-yl]...)
Affinity DataIC50: 190nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347516BDBM347516(4-{[3-(2,4-Dichlorophenyl)piperidin-1-yl]carbonyl}...)
Affinity DataIC50: 190nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347602BDBM347602(3-(4-Chloro-2-methylphenyl)-1-[(1,3-dimethyl-1H-py...)
Affinity DataIC50: 200nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347597BDBM347597(5-({3-[4-Methoxy-2-(trifluoromethyl)phenyl]piperid...)
Affinity DataIC50: 210nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347559BDBM347559(N,N-Dimethyl-4-({3-[2-(trifluoromethyl)phenyl]pipe...)
Affinity DataIC50: 220nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347568BDBM347568(N-Methyl-4-({3-[2-(trifluoromethyl)phenyl]piperidi...)
Affinity DataIC50: 230nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347530BDBM347530(4-{[3-(4-Chlorophenyl)piperidin-1-yl]carbonyl}-N,N...)
Affinity DataIC50: 270nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347620BDBM347620(4-{[5-(4-Chloro-2-methylphenyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 270nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347520BDBM347520(4-({3-[4-Chloro-2-(trifluoromethyl)phenyl]piperidi...)
Affinity DataIC50: 280nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347525BDBM347525(US9790201, 49 | 3-Chloro-5-{[3-(2-methoxyphenyl)pi...)
Affinity DataIC50: 290nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347525BDBM347525(US9790201, 49 | 3-Chloro-5-{[3-(2-methoxyphenyl)pi...)
Affinity DataIC50: 310nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347614BDBM347614(3-[4-Chloro-2-(trifluoromethyl)phenyl]-1-{[1-(prop...)
Affinity DataIC50: 330nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347615BDBM347615(US9790201, 118 | US9790201, 119 | 4-({3-[4-Chloro-...)
Affinity DataIC50: 330nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347589BDBM347589(5-{[3-(4-Chloro-2-methylphenyl)piperidin-1-yl]carb...)
Affinity DataIC50: 350nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347569BDBM347569(4-{[3-(4-Methoxyphenyl)piperidin-1-yl]carbonyl}-N-...)
Affinity DataIC50: 350nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347562BDBM347562(4-{[3-(2-Methoxyphenyl)piperidin-1-yl]carbonyl}-N,...)
Affinity DataIC50: 410nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347525BDBM347525(US9790201, 49 | 3-Chloro-5-{[3-(2-methoxyphenyl)pi...)
Affinity DataIC50: 420nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347619BDBM347619(4-{[5-(4-Chlorophenyl)-1,2,3,4-tetrahydropyridin-1...)
Affinity DataIC50: 420nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347626BDBM347626(4-{[3-(4-Chlorophenyl)azepan-1-yl]carbonyl}-N-meth...)
Affinity DataIC50: 430nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347570BDBM347570(4-{[3-(2-Methoxyphenyl)piperidin-1-yl]carbonyl}-N-...)
Affinity DataIC50: 440nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetProkineticin receptor 1(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 347625BDBM347625(4-{[3-(4-Methoxyphenyl)azepan-1-yl]carbonyl}-N-met...)
Affinity DataIC50: 450nMAssay Description:Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

Displayed 1 to 50 (of 119 total ) | Next | Last >>
Jump to: