Compile Data Set for Download or QSAR
Report error Found 212 Enz. Inhib. hit(s) with all data for entry = 1964
TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348693BDBM348693(N-(4-Chlorophenyl)-4-[(1S,3R,4S)-2-oxa-5-azabicycl...)
Affinity DataIC50: 0.700nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348694BDBM348694(N-(4-Bromophenyl)-4-[(1S,3R,4S)-2-oxa-5-azabicyclo...)
Affinity DataIC50: 0.900nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348696BDBM348696(N-(4-Ethoxyphenyl)-4-[(1S,3R,4S)-2-oxa-5-azabicycl...)
Affinity DataIC50: 1.30nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348697BDBM348697(4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3-yl...)
Affinity DataIC50: 2.20nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348727BDBM348727(2-Isopropyl-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2....)
Affinity DataIC50: 2.60nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348641BDBM348641(1-[3-[(1R,3S,4R)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...)
Affinity DataIC50: 2.90nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348706BDBM348706(4-Chloro-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 3.10nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348698BDBM348698(N-(6-Chloro-3-pyridyl)-4-[(1S,3R,4S)-2-oxa-5-azabi...)
Affinity DataIC50: 3.30nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348730BDBM348730(3-Butyl-4-fluoro-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyc...)
Affinity DataIC50: 3.30nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348662BDBM348662(5-Chloro-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 3.30nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348702BDBM348702(N-[(4-Chlorophenyl)methyl]-4-[(1S,3R,4S)-2-oxa-5-a...)
Affinity DataIC50: 3.30nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348691BDBM348691((1S,3R,4S)-3-(4-Bromophenyl)-2-oxa-5-azabicyclo[2....)
Affinity DataIC50: 3.40nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348701BDBM348701(4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3-yl...)
Affinity DataIC50: 3.40nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348695BDBM348695(N-(4-Fluorophenyl)-4-[(1S,3R,4S)-2-oxa-5-azabicycl...)
Affinity DataIC50: 3.40nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348689BDBM348689(N-[4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...)
Affinity DataIC50: 3.40nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348671BDBM348671(1-(4-Chlorophenyl)-3-[4-[(1S,3R,4S)-2-oxa-5-azabic...)
Affinity DataIC50: 3.5nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348737BDBM348737(4-Bromo-3-ethyl-N-[4-[(1R,3S,4R)-2-oxa-5-azabicycl...)
Affinity DataIC50: 3.5nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348720BDBM348720(4-Chloro-3-cyclopropyl-N-[4-[(1R,3S,4R)-2-oxa-5-az...)
Affinity DataIC50: 3.5nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348649BDBM348649(N-[4-[(1R,3S,4R)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...)
Affinity DataIC50: 3.90nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348658BDBM348658(5-Chloro-N-[4-[(1S,3R,4S)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 4.10nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348683BDBM348683(4-Chloro-3-ethoxy-N-[4-[(1S,3R,4S)-2-oxa-5-azabicy...)
Affinity DataIC50: 4.20nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348731BDBM348731(3-Butyl-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1]...)
Affinity DataIC50: 4.20nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348716BDBM348716(4-Fluoro-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 4.20nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348648BDBM348648(3-Chloro-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 4.20nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348666BDBM348666(4-Ethoxy-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 4.30nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348690BDBM348690(4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3-yl...)
Affinity DataIC50: 4.30nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348645BDBM348645(4-Chloro-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 4.40nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348687BDBM348687(4-Chloro-N-[4-[(1S,3R,4S)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 4.40nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348646BDBM348646(3-Chloro-N-[4-[(1S,3R,4S)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 4.60nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348714BDBM348714(4-Chloro-3-ethyl-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyc...)
Affinity DataIC50: 4.70nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348715BDBM348715(3-Cyclopropyl-4-fluoro-N-[4-[(1R,3S,4R)-2-oxa-5-az...)
Affinity DataIC50: 4.80nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348700BDBM348700(N-(6-Ethoxy-3-pyridyl)-4-[(1S,3R,4S)-2-oxa-5-azabi...)
Affinity DataIC50: 4.90nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348652BDBM348652(4-Chloro-N-[4-[(1S,3R,4S)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 5nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348691BDBM348691((1S,3R,4S)-3-(4-Bromophenyl)-2-oxa-5-azabicyclo[2....)
Affinity DataIC50: 5.20nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348709BDBM348709(N-[4-[(1R,3S,4R)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...)
Affinity DataIC50: 5.40nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348739BDBM348739(3-Isobutyl-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2...)
Affinity DataIC50: 5.70nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348738BDBM348738(4-Fluoro-3-isobutyl-N-[4-[(1R,3S,4R)-2-oxa-5-azabi...)
Affinity DataIC50: 5.90nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348717BDBM348717(N-[4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...)
Affinity DataIC50: 6nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348651BDBM348651(6-Ethoxy-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 6.30nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348670BDBM348670(4-(Cyclopropylmethoxy)-N-[4-[(1S,3R,4S)-2-oxa-5-az...)
Affinity DataIC50: 6.30nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348655BDBM348655(4-Ethoxy-N-[4-[(1S,3R,4S)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50: 6.40nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348707BDBM348707(3-Cyclopropyl-4-methyl-N-[4-[(1R,3S,4R)-2-oxa-5-az...)
Affinity DataIC50: 6.60nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348650BDBM348650(4-(Cyclopropylmethoxy)-N-[4-[(1R,3S,4R)-2-oxa-5-az...)
Affinity DataIC50: 6.70nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348736BDBM348736(4-Chloro-3-ethoxy-N-[4-[(1R,3S,4R)-2-oxa-5-azabicy...)
Affinity DataIC50: 6.80nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348677BDBM348677(4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3-yl...)
Affinity DataIC50: 6.90nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348657BDBM348657(N-[4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...)
Affinity DataIC50: 7.10nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348660BDBM348660(N-[4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...)
Affinity DataIC50: 7.60nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348699BDBM348699(N-[4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...)
Affinity DataIC50: 7.70nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348718BDBM348718(N-[4-[(1S,3R,4S)-2-Oxa-5-azabicyclo[2.2.1]heptan-3...)
Affinity DataIC50: 7.70nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 348740BDBM348740(4-Chloro-3-isopropyl-N-[4-[(1R,3S,4R)-2-oxa-5-azab...)
Affinity DataIC50: 8.90nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent

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