Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 2074
LigandChemical structure of BindingDB Monomer ID 197759BDBM197759(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 4nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 350358BDBM350358(US9801878, 2-[2-(5,7-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 12nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197757BDBM197757(US9216986, 2-[(E)-2-(5,8-Dimethyl-[1,2,4]triazolo[...)
Affinity DataIC50: 13nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197747BDBM197747(US9216986, 2-[2-(8-Methoxy-5-methyl-[1,2,4]triazol...)
Affinity DataIC50: 15nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197741BDBM197741(US9216986, 2-[2-(6-Fluoro-quinolin-2-yl)-ethyl]-5-...)
Affinity DataIC50: 18nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197763BDBM197763(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 19nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197734BDBM197734(BDBM197735 | US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]...)
Affinity DataIC50: 19nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197748BDBM197748(US9216986, 4-Chloro-8-fluoro-2-[(E)-2-(8-methoxy-5...)
Affinity DataIC50: 24nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197739BDBM197739(US9216986, 6-Fluoro-2-[2-(8-methoxy-5-methyl-[1,2,...)
Affinity DataIC50: 24nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197737BDBM197737(US9216986, 2-[2-(8-Methoxy-5-methyl-[1,2,4]triazol...)
Affinity DataIC50: 25nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197738BDBM197738(US9216986, 2-[2-(8-Ethyl-5-methyl-[1,2,4]triazolo[...)
Affinity DataIC50: 34nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197743BDBM197743(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 35nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197762BDBM197762(US9216986, 7-Chloro-2-[2-(5,8-dimethyl-[1,2,4]tria...)
Affinity DataIC50: 39nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197760BDBM197760(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 42nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197751BDBM197751(BDBM197752 | US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]...)
Affinity DataIC50: 52nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197753BDBM197753(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 61nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197733BDBM197733(US9216986, 2-[2-(5,7-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 72nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197740BDBM197740(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 85nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197754BDBM197754(US9216986, 2-[(E)-2-(5,8-Dimethyl-[1,2,4]triazolo[...)
Affinity DataIC50: 110nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197751BDBM197751(BDBM197752 | US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]...)
Affinity DataIC50: 120nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197744BDBM197744(US9216986, 4-Methoxy-2-[2-(5-methyl-[1,2,4]triazol...)
Affinity DataIC50: 140nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197746BDBM197746(US9216986, 4-Methyl-2-[2-(5-methyl-[1,2,4]triazolo...)
Affinity DataIC50: 150nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197734BDBM197734(BDBM197735 | US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]...)
Affinity DataIC50: 170nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197749BDBM197749(US9216986, 8-Fluoro-2-[2-(8-methoxy-5-methyl-[1,2,...)
Affinity DataIC50: 190nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197742BDBM197742(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 190nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197731BDBM197731(US9216986, 2-[(Z)-2-(5,7-Dimethyl-imidazo[1,2-a]py...)
Affinity DataIC50: 240nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197745BDBM197745(US9216986, 4-Methoxy-2-[2-(8-methoxy-5-methyl-[1,2...)
Affinity DataIC50: 270nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197761BDBM197761(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 290nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197756BDBM197756(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 300nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197732BDBM197732(US9216986, 2-[2-(5,7-Dimethyl-imidazo[1,2-a]pyrimi...)
Affinity DataIC50: 310nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197730BDBM197730(US9216986, 2-[(E)-2-(5,7-Dimethyl-imidazo[1,2-a]py...)
Affinity DataIC50: 320nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197755BDBM197755(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 360nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197758BDBM197758(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 520nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 197750BDBM197750(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 550nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent