Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 2104
TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352439BDBM352439(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352440BDBM352440(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352437BDBM352437(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352438BDBM352438(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352443BDBM352443(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352444BDBM352444(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352441BDBM352441(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352442BDBM352442(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352431BDBM352431(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352429BDBM352429(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352435BDBM352435(US9808445, 11.2 | N-((1S*,4S*,7R*)-2-(3-Amino-5-me...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352433BDBM352433(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352434BDBM352434(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352453BDBM352453(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352454BDBM352454(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352447BDBM352447(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352448BDBM352448(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352445BDBM352445(4-([1,2,4]Triazolo[4,3-a]pyridin-6-yl)-N-((1S*,4S*...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352446BDBM352446(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352451BDBM352451(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352452BDBM352452(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352449BDBM352449(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352450BDBM352450(N-((1S*,4S*,7R*)-2-(3-Amino-5-cyanoisoxazolo[5,4-c...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352422BDBM352422(N-((1S*,4S*, 7R*)-2-(3-Aminobenzo[d]isoxazol-7-yl)...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352423BDBM352423(N-((1S*,4S*,7R*)-2-(3-Aminoisoxazolo[5,4-c]pyridin...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352427BDBM352427(N-((1S*,4S*,7R*)-2-(3-Amino-4-chlorobenzo[d]isoxaz...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352428BDBM352428(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352424BDBM352424(N-((1S*,4S*,7R*)-2-(3-Amino-5-methylbenzo[d]isoxaz...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352425BDBM352425(N-((1S*,4S*,7R*)-2-(3-Amino-5-chlorobenzo[d]isoxaz...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352432BDBM352432(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352429BDBM352429(N-((1S*,4S*,7R*)-2-(3-Amino-4-chloroisoxazolo[5,4-...)
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent

TargetCoagulation factor IX(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 352435BDBM352435(US9808445, 11.2 | N-((1S*,4S*,7R*)-2-(3-Amino-5-me...)
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against factor IXa was tested using the substrate SPECTROFLUOR FIXa (american diagnostica inc.; 500 West Avenue, Stamford, Conn. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details
US Patent