Compile Data Set for Download or QSAR
Report error Found 117 Enz. Inhib. hit(s) with all data for entry = 614
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282619BDBM282619(US9884828, 2-114)
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282625BDBM282625(US9884828, 2-120)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282616BDBM282616(US9884828, 2-111)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282670BDBM282670(US9884828, 9-213)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282606BDBM282606(US9884828, 2-101)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282626BDBM282626(US9884828, 2-121)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428717BDBM50428717(CHEMBL2333127 | US9884828, 2-37)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428716BDBM50428716(CHEMBL2333128 | US9884828, 2-41)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428701BDBM50428701(CHEMBL2333115 | US9884828, 2-127)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282617BDBM282617(US9884828, 2-112)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428703BDBM50428703(CHEMBL2333113 | US9884828, 2-100)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282607BDBM282607(US9884828, 2-102)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282627BDBM282627(US9884828, 2-122)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282674BDBM282674(US9884828, 11-221)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428698BDBM50428698(CHEMBL2333118 | US9884828, 2-35)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282589BDBM282589(US9884828, 2-49)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428700BDBM50428700(CHEMBL2333116 | US9884828, 2-53)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282615BDBM282615(US9884828, 2-110)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428715BDBM50428715(CHEMBL2333129 | US9884828, 2-19)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282621BDBM282621(US9884828, 2-116)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282623BDBM282623(US9884828, 2-118)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282611BDBM282611(US9884828, 2-106)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282661BDBM282661(US9884828, 5-55)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428704BDBM50428704(CHEMBL2333112 | US9884828, 2-31)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428718BDBM50428718(CHEMBL2333126 | US9884828, 2-17)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428714BDBM50428714(CHEMBL2333130 | US9884828, 2-92)
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428710BDBM50428710(CHEMBL2333134 | US9884828, 2-23)
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282590BDBM282590(US9884828, 2-51)
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282624BDBM282624(US9884828, 2-119)
Affinity DataIC50: 18nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428712BDBM50428712(CHEMBL2333132 | US9884828, 2-25)
Affinity DataIC50: 23nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282673BDBM282673(US9884828, 11-220)
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282639BDBM282639(US9884828, 2-134)
Affinity DataIC50: 26nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428702BDBM50428702(CHEMBL2333114 | US9884828, 2-126)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282658BDBM282658(US9884828, 4-190)
Affinity DataIC50: 31nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282654BDBM282654(US9884828, 4-80)
Affinity DataIC50: 31nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282592BDBM282592(US9884828, 2-57)
Affinity DataIC50: 33nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282672BDBM282672(US9884828, 11-218)
Affinity DataIC50: 43nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282596BDBM282596(US9884828, 2-91)
Affinity DataIC50: 45nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428713BDBM50428713(CHEMBL2333131 | US9884828, 2-93)
Affinity DataIC50: 46nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282602BDBM282602(US9884828, 2-97)
Affinity DataIC50: 46nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428711BDBM50428711(CHEMBL2333133 | US9884828, 2-29)
Affinity DataIC50: 47nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282612BDBM282612(US9884828, 2-107)
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282620BDBM282620(US9884828, 2-115)
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282678BDBM282678(US9884828, 13-233)
Affinity DataIC50: 51nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282618BDBM282618(US9884828, 2-113)
Affinity DataIC50: 51nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50428697BDBM50428697(CHEMBL2333119 | US9884828, 4-188)
Affinity DataIC50: 53nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282665BDBM282665(US9884828, 9-206)
Affinity DataIC50: 54nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282586BDBM282586(US9884828, 2-43)
Affinity DataIC50: 55nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282595BDBM282595(US9884828, 2-90)
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Imago Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 282668BDBM282668(US9884828, 9-209)
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

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