Compile Data Set for Download or QSAR
Report error Found 109 Enz. Inhib. hit(s) with all data for entry = 2962
TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387085BDBM387085(3-(7-Oxo-6-(1-(3-oxomorpholino)piperidin-4-yl)-3-(...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387083BDBM387083(4-(4-(1-(3-Fluoronaphthalen-2-yl)-7-oxo-3-(trifluo...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387058BDBM387058(1-(4-Methoxyphenyl)-7-oxo-6-(1-(3-oxomorpholino)pi...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387059BDBM387059(US9938272, Example 8b | US9938272, Example 8a)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387058BDBM387058(1-(4-Methoxyphenyl)-7-oxo-6-(1-(3-oxomorpholino)pi...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387057BDBM387057(N′-Cyano-1-(4-methoxyphenyl)-7-oxo-6-(2̸...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387056BDBM387056(1-(4-Methoxyphenyl)-7-oxo-6-(2′-oxo-[1,1R...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387082BDBM387082(4-(4-(1-(3-Fluoro-4-methoxyphenyl)-7-oxo-3-(triflu...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387082BDBM387082(4-(4-(1-(3-Fluoro-4-methoxyphenyl)-7-oxo-3-(triflu...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387057BDBM387057(N′-Cyano-1-(4-methoxyphenyl)-7-oxo-6-(2̸...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387083BDBM387083(4-(4-(1-(3-Fluoronaphthalen-2-yl)-7-oxo-3-(trifluo...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387083BDBM387083(4-(4-(1-(3-Fluoronaphthalen-2-yl)-7-oxo-3-(trifluo...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387082BDBM387082(4-(4-(1-(3-Fluoro-4-methoxyphenyl)-7-oxo-3-(triflu...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387065BDBM387065(1-(4-(Difluoromethoxy)phenyl)-7-oxo-6-(1-(3-oxomor...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387065BDBM387065(1-(4-(Difluoromethoxy)phenyl)-7-oxo-6-(1-(3-oxomor...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387064BDBM387064(7-Oxo-6-(1-(3-oxomorpholino)piperidin-4-yl)-1-(4-(...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387049BDBM387049(4-(4-(1-(4-Methoxyphenyl)-7-oxo-3-(trifluoromethyl...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387049BDBM387049(4-(4-(1-(4-Methoxyphenyl)-7-oxo-3-(trifluoromethyl...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 19023BDBM19023(BMS-562247 | CHEMBL231779 | 1-(4-methoxyphenyl)-7-...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387077BDBM387077(4-(4-(1-(4-(Difluoromethoxy)phenyl)-7-oxo-3-(trifl...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387050BDBM387050(1-(4-Methoxyphenyl)-6-(2′-oxo-[1,1′-bi...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387049BDBM387049(4-(4-(1-(4-Methoxyphenyl)-7-oxo-3-(trifluoromethyl...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387068BDBM387068(1-(4-Methoxyphenyl)-7-oxo-6-(2-oxo-[1,4′-bip...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387068BDBM387068(1-(4-Methoxyphenyl)-7-oxo-6-(2-oxo-[1,4′-bip...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 19023BDBM19023(BMS-562247 | CHEMBL231779 | 1-(4-methoxyphenyl)-7-...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387080BDBM387080(4-(4-(1-(3-Aminobenzo[d]isoxazol-5-yl)-7-oxo-3-(tr...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387080BDBM387080(4-(4-(1-(3-Aminobenzo[d]isoxazol-5-yl)-7-oxo-3-(tr...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387055BDBM387055(1-(4-Methoxyphenyl)-7-oxo-6-(2′-oxo-[1,1R...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387078BDBM387078(4-(4-(1-(6-Chloronaphthalen-2-yl)-7-oxo-3-(trifluo...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387054BDBM387054(1-(4-Methoxyphenyl)-6-(1-(2-oxopyrrolidin-1-yl)pip...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387080BDBM387080(4-(4-(1-(3-Aminobenzo[d]isoxazol-5-yl)-7-oxo-3-(tr...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387055BDBM387055(1-(4-Methoxyphenyl)-7-oxo-6-(2′-oxo-[1,1R...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387077BDBM387077(4-(4-(1-(4-(Difluoromethoxy)phenyl)-7-oxo-3-(trifl...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387050BDBM387050(1-(4-Methoxyphenyl)-6-(2′-oxo-[1,1′-bi...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387050BDBM387050(1-(4-Methoxyphenyl)-6-(2′-oxo-[1,1′-bi...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387078BDBM387078(4-(4-(1-(6-Chloronaphthalen-2-yl)-7-oxo-3-(trifluo...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387054BDBM387054(1-(4-Methoxyphenyl)-6-(1-(2-oxopyrrolidin-1-yl)pip...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387078BDBM387078(4-(4-(1-(6-Chloronaphthalen-2-yl)-7-oxo-3-(trifluo...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387054BDBM387054(1-(4-Methoxyphenyl)-6-(1-(2-oxopyrrolidin-1-yl)pip...)
Affinity DataKi: <10nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387058BDBM387058(1-(4-Methoxyphenyl)-7-oxo-6-(1-(3-oxomorpholino)pi...)
Affinity DataKi:  30nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387085BDBM387085(3-(7-Oxo-6-(1-(3-oxomorpholino)piperidin-4-yl)-3-(...)
Affinity DataKi:  30nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387059BDBM387059(US9938272, Example 8b | US9938272, Example 8a)
Affinity DataKi:  30nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387074BDBM387074(N5-(1-(3-Oxomorpholino)piperidin-4-yl)-1-(tetrahyd...)
Affinity DataKi:  30nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387085BDBM387085(3-(7-Oxo-6-(1-(3-oxomorpholino)piperidin-4-yl)-3-(...)
Affinity DataKi:  30nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387067BDBM387067(1-(4-Methoxyphenyl)-7-oxo-6-(3-(3-oxomorpholino)-3...)
Affinity DataKi:  30nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 387069BDBM387069(1-(4-Methoxyphenyl)-N5-(1-(3-oxomorpholino)piperid...)
Affinity DataKi:  30nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Human)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387069BDBM387069(1-(4-Methoxyphenyl)-N5-(1-(3-oxomorpholino)piperid...)
Affinity DataKi:  30nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 19023BDBM19023(BMS-562247 | CHEMBL231779 | 1-(4-methoxyphenyl)-7-...)
Affinity DataKi:  30nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387057BDBM387057(N′-Cyano-1-(4-methoxyphenyl)-7-oxo-6-(2̸...)
Affinity DataKi:  30nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetCoagulation factor X(Rat)
North China Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 387065BDBM387065(1-(4-(Difluoromethoxy)phenyl)-7-oxo-6-(1-(3-oxomor...)
Affinity DataKi:  30nMAssay Description:Factor Xa (human or rat): In the assay for measuring the inhibition of human or rat factor Xa activity, Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

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