Compile Data Set for Download or QSAR
Report error Found 205 Enz. Inhib. hit(s) with all data for entry = 3022
TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388831BDBM388831(US9944645, 161 | N-Cyclopropyl-2-fluoro-4-[7-(1-qu...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388830BDBM388830(US9944645, 160 | 2-Fluoro-N-methyl-4-[7-(1-quinoli...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388829BDBM388829(US9944645, 159 | 2-Fluoro-N-(trans-4-hydroxycycloh...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388828BDBM388828(US9944645, 158 | 2-Fluoro-N-[1-(hydroxymethyl)cycl...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388835BDBM388835(US9944645, 165 | 2-Fluoro-N-(pyridin-2-ylmethyl)-4...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388834BDBM388834(US9944645, 164 | 6-{1-[6-(3-Fluoro-4-[(3S)-3-fluor...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388833BDBM388833(US9944645, 163 | 2-Fluoro-N-(2-methoxy-1-methyleth...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388832BDBM388832(US9944645, 162 | 2-Fluoro-N-[1-(methoxymethyl)cycl...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388823BDBM388823(US9944645, 153 | 2-Fluoro-N-(pyridin-4-ylmethyl)-4...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388822BDBM388822(US9944645, 152 | 2-Fluoro-N-(pyridin-3-ylmethyl)-4...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388821BDBM388821(US9944645, 151 | 2-Fluoro-N-(pyridin-2-ylmethyl)-4...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388820BDBM388820(US9944645, 150 | 2-Fluoro-N-[2-(1-methylpyrrolidin...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388827BDBM388827(US9944645, 157 | 2-Fluoro-N-[(1S)-1-(hydroxymethyl...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388826BDBM388826(US9944645, 156 | 2-Fluoro-N-(1-pyridin-4-ylethyl)-...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388825BDBM388825(US9944645, 155 | 2-Fluoro-N-(1-pyridin-3-ylethyl)-...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388824BDBM388824(US9944645, 154 | 2-Fluoro-N-(2-pyridin-2-ylethyl)-...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388847BDBM388847(US9944645, 177 | 2-Chloro-N-(1-pyridin-2-ylethyl)-...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388846BDBM388846(US9944645, 176 | 2-Chloro-4-[3-(1-quinolin-6-ylcyc...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388845BDBM388845(US9944645, 175 | 2-Chloro-N-cyclopropyl-4-[3-(1-qu...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388844BDBM388844(US9944645, 174 | 2-Chloro-N-methyl-4-[3-(1-quinoli...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388851BDBM388851(US9944645, 181 | 2-Chloro-N-(1S)-1-[(dimethylamino...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388850BDBM388850(US9944645, 180 | 2-Chloro-N-[1-methyl-2-(pyridin-2...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388849BDBM388849(US9944645, 179 | 2-Chloro-N-(1-pyridin-2-ylpyrroli...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388848BDBM388848(US9944645, 178 | 6-(1-{6-[4-(Azetidin-1-ylcarbonyl...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388839BDBM388839(US9944645, 169 | 2-Fluoro-4-[3-(1-quinolin-6-ylcyc...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388838BDBM388838(US9944645, 168 | 2-Fluoro-4-[3-(1-quinolin-6-ylcyc...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388837BDBM388837(US9944645, 167 | 2-Fluoro-N-(1-pyridin-2-ylpyrroli...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388836BDBM388836(US9944645, 166 | 2-Fluoro-N-(1-pyridin-2-ylcyclopr...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388843BDBM388843(US9944645, 173 | 2-Fluoro-N-methyl-N-2-[methyl(pyr...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388842BDBM388842(US9944645, 172 | 2-Fluoro-4-[3-(1-quinolin-6-ylcyc...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388841BDBM388841(US9944645, 171 | 2-Fluoro-N-[(1S)-1-(methoxymethyl...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388840BDBM388840(US9944645, 170 | N-Cyclopropyl-2-fluoro-4-[3-(1-qu...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388863BDBM388863(US9944645, 193 | 2-(2,3-Dichlorophenyl)-7-(1-quino...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388862BDBM388862(US9944645, 192 | N-(3-[2-(4-Bromo-3-fluorophenyl)i...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388861BDBM388861(US9944645, 191 | 2-{2-fluoro-4-[3-(1-quinolin-6-yl...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388860BDBM388860(US9944645, 190 | 2-{2-Fluoro-4-[3-(1-quinolin-6-yl...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388867BDBM388867(US9944645, 197 | N,N-Dimethyl-2-{3-[3-(1-quinolin-...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388866BDBM388866(US9944645, 196 | 2-Fluoro-N-methyl-4-[3-(1-quinoli...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388865BDBM388865(US9944645, 195 | 6-Difluoro-N-methyl-4-[3-(1-quino...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388864BDBM388864(US9944645, 194 | 2,3-Difluoro-N-methyl-4-[3-(1-qui...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388855BDBM388855(US9944645, 185 | 2-(Pyridin-2-ylmethyl)-5-[3-(1-qu...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388854BDBM388854(US9944645, 184 | 2-(2-Methoxy-1-methylethyl)-5-[3-...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388853BDBM388853(US9944645, 183 | 2-Ethyl-5-[3-(1-quinolin-6-ylcycl...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388852BDBM388852(US9944645, 182 | 2-Cyclopropyl-5-[3-(1-quinolin-6-...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388859BDBM388859(US9944645, 189 | N-[1-Methyl-2-(pyridin-2-yloxy)et...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388858BDBM388858(US9944645, 188 | N-(1-Pyridin-2-ylethyl)-1-{4-[3-(...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388857BDBM388857(US9944645, 187 | N-Ethyl-1-{4-[3-(1-quinolin-6-ylc...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388856BDBM388856(US9944645, 186 | 2-Methyl-5-[3-(1-quinolin-6-ylcyc...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388871BDBM388871(US9944645, 201 | 2-Fluoro-N-2-[(3R)-3-methoxypyrro...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 388870BDBM388870(US9944645, 200 | N-(2-Azetidin-1-yl-1-methyl-2-oxo...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

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