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Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 3303
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396920BDBM396920(US9981963, Compound 11)
Affinity DataIC50: 6nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396916BDBM396916(US9981963, Compound 7)
Affinity DataIC50: 9nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396918BDBM396918(US9981963, Compound 9)
Affinity DataIC50: 9nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396919BDBM396919(US9981963, Compound 10)
Affinity DataIC50: 9nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396936BDBM396936(US9981963, Compound 31)
Affinity DataIC50: 9nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396924BDBM396924(US9981963, Compound 15)
Affinity DataIC50: 10nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396922BDBM396922(US9981963, Compound 13)
Affinity DataIC50: 14nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396934BDBM396934(US9981963, Compound 25)
Affinity DataIC50: 14nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396914BDBM396914(US9981963, Compound 5)
Affinity DataIC50: 16nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396923BDBM396923(US9981963, Compound 14)
Affinity DataIC50: 18nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396915BDBM396915(US9981963, Compound 6)
Affinity DataIC50: 19nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396917BDBM396917(US9981963, Compound 8)
Affinity DataIC50: 21nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396913BDBM396913(US9981963, Compound 4)
Affinity DataIC50: 28nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396929BDBM396929(US9981963, Compound 20)
Affinity DataIC50: 29nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396935BDBM396935(US9981963, Compound 30)
Affinity DataIC50: 29nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396927BDBM396927(US9981963, Compound 18)
Affinity DataIC50: 45nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396921BDBM396921(US9981963, Compound 12)
Affinity DataIC50: 47nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396933BDBM396933(US9981963, Compound 24)
Affinity DataIC50: 48nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396930BDBM396930(US9981963, Compound 21)
Affinity DataIC50: 55nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396932BDBM396932(US9981963, Compound 23)
Affinity DataIC50: 57nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396912BDBM396912(US9981963, Compound 3)
Affinity DataIC50: 58nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396910BDBM396910(US9981963, Compound 1)
Affinity DataIC50: 60nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396928BDBM396928(US9981963, Compound 19)
Affinity DataIC50: 65nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396937BDBM396937(US9981963, Compound 32)
Affinity DataIC50: 68nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396938BDBM396938(US9981963, Compound 34)
Affinity DataIC50: 76nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396926BDBM396926(US9981963, Compound 17)
Affinity DataIC50: 88nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396925BDBM396925(US9981963, Compound 16)
Affinity DataIC50: 92nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396911BDBM396911(US9981963, Compound 2)
Affinity DataIC50: 129nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 396931BDBM396931(US9981963, Compound 22)
Affinity DataIC50: 224nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent