Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 3335
TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397466BDBM397466(US9988392, Compound 10)
Affinity DataEC50:  0.0370nMAssay Description:κ-Opioid: Receptor Binding Assay Procedures: Membranes from HEK-293, CHO or U-2 OS cells expressing the recombinant human kappa opioid receptor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397187BDBM397187(US9988392, Compound 7)
Affinity DataEC50:  0.0470nMAssay Description:κ-Opioid: Receptor Binding Assay Procedures: Membranes from HEK-293, CHO or U-2 OS cells expressing the recombinant human kappa opioid receptor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397187BDBM397187(US9988392, Compound 7)
Affinity DataEC50:  0.0640nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397186BDBM397186(US9988392, Compound 6)
Affinity DataEC50:  0.0850nMAssay Description:κ-Opioid: Receptor Binding Assay Procedures: Membranes from HEK-293, CHO or U-2 OS cells expressing the recombinant human kappa opioid receptor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397466BDBM397466(US9988392, Compound 10)
Affinity DataEC50:  0.130nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397188BDBM397188(US9988392, Compound 8)
Affinity DataEC50:  0.140nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397472BDBM397472(US9988392, Compound 18)
Affinity DataEC50:  0.240nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397188BDBM397188(US9988392, Compound 8)
Affinity DataEC50:  0.270nMAssay Description:κ-Opioid: Receptor Binding Assay Procedures: Membranes from HEK-293, CHO or U-2 OS cells expressing the recombinant human kappa opioid receptor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397470BDBM397470(US9988392, Compound 16)
Affinity DataEC50:  0.360nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397187BDBM397187(US9988392, Compound 7)
Affinity DataEC50:  0.550nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397467BDBM397467(US9988392, Compound 12 | (4R,4aS,6R,7R,7aR,12bS)-6...)
Affinity DataEC50:  3.39nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397474BDBM397474(US9988392, Compound 20)
Affinity DataEC50:  3.46nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397186BDBM397186(US9988392, Compound 6)
Affinity DataEC50:  8.81nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397468BDBM397468(US9988392, Compound 13)
Affinity DataEC50:  14.6nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397448BDBM397448(US9988392, Compound 9)
Affinity DataEC50:  15.1nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397469BDBM397469(US9988392, Compound 15)
Affinity DataEC50:  16.5nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397186BDBM397186(US9988392, Compound 6)
Affinity DataEC50:  57.7nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397471BDBM397471(US9988392, Compound 17)
Affinity DataEC50:  74.2nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397473BDBM397473(US9988392, Compound 19)
Affinity DataEC50:  402nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397188BDBM397188(US9988392, Compound 8)
Affinity DataEC50:  1.34E+4nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 397466BDBM397466(US9988392, Compound 10)
Affinity DataEC50: >2.00E+4nMAssay Description:μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2020
Entry Details
US Patent