Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 10440
TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535166BDBM535166(WO2022013684, Example 18)
Affinity DataKi:  1.55nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535159BDBM535159(WO2022013684, Example 14)
Affinity DataKi:  6.02nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535160BDBM535160(WO2022013684, Example 15)
Affinity DataKi:  6.14nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535126BDBM535126((1R,2S,5S)-6,6-Dimethyl-3-[N-(methylsulfonyl)-L-va...)
Affinity DataKi:  7.74nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535168BDBM535168(WO2022013684, Example 19)
Affinity DataKi:  9.77nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535164BDBM535164(WO2022013684, Example 16)
Affinity DataKi:  10nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535123BDBM535123((1R,2S,5S)-N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo...)
Affinity DataKi:  11nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535143BDBM535143(WO2022013684, Example 11)
Affinity DataKi:  14nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535129BDBM535129((1R,2S,5S)-N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo...)
Affinity DataKi:  15nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535141BDBM535141(WO2022013684, Example 10)
Affinity DataKi:  20nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535075BDBM535075((6S)-N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo-3-[(3...)
Affinity DataKi:  20nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535145BDBM535145(WO2022013684, Example 12)
Affinity DataKi:  34nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535165BDBM535165(WO2022013684, Example 17)
Affinity DataKi:  99nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535166BDBM535166(WO2022013684, Example 18)
Affinity DataEC50:  129nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535130BDBM535130(tert-Butyl {(2S)-1-[(1R,2S,5S)-2-({(2S)-1-(1,3-ben...)
Affinity DataKi:  137nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535146BDBM535146(WO2022013684, Example 13)
Affinity DataKi:  139nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535143BDBM535143(WO2022013684, Example 11)
Affinity DataEC50:  155nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535122BDBM535122((1R,2S,5S)-N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo...)
Affinity DataKi:  206nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535130BDBM535130(tert-Butyl {(2S)-1-[(1R,2S,5S)-2-({(2S)-1-(1,3-ben...)
Affinity DataEC50:  492nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535165BDBM535165(WO2022013684, Example 17)
Affinity DataEC50:  584nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535129BDBM535129((1R,2S,5S)-N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo...)
Affinity DataEC50:  697nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535123BDBM535123((1R,2S,5S)-N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo...)
Affinity DataEC50:  1.21E+3nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535168BDBM535168(WO2022013684, Example 19)
Affinity DataEC50:  1.33E+3nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535075BDBM535075((6S)-N-{(2S)-1-(1,3-Benzothiazol-2-yl)-1-oxo-3-[(3...)
Affinity DataEC50:  5.68E+3nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535131BDBM535131(WO2022013684, Example 8)
Affinity DataKi:  6.33E+3nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535140BDBM535140(WO2022013684, Example 9)
Affinity DataKi: >1.00E+4nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandChemical structure of BindingDB Monomer ID 535170BDBM535170(WO2022013684, Example 20)
Affinity DataKi: >1.08E+4nMAssay Description:The proteolytic activity of the main protease, 3CLpro, of SARS-CoV-2 was monitored using a continuous fluorescence resonance energy transfer (FRET) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
WIPO WO2022013684