Compile Data Set for Download or QSAR
Report error Found 137 Enz. Inhib. hit(s) with all data for entry = 13311
TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776298(4-[(4R,7S,8R)-17-({[(7aS)-2-(difluoromethylene)-2,...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776298(4-[(4R,7S,8R)-17-({[(7aS)-2-(difluoromethylene)-2,...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776297((4R,11S,14aR)-11-(2-amino-3-cyano-7-fluorobenzo[b]...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776297((4R,11S,14aR)-11-(2-amino-3-cyano-7-fluorobenzo[b]...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776296((4R,11R,14aR)-11-(2-amino-3-cyano-7-fluorobenzo[b]...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776296((4R,11R,14aR)-11-(2-amino-3-cyano-7-fluorobenzo[b]...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776295(4-((4R,14aR)-12-chloro-8-(((S)-2-(difluoromethylen...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776295(4-((4R,14aR)-12-chloro-8-(((S)-2-(difluoromethylen...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776301(6-((4R,11R,14aR)-12-chloro-8-(((3S,4S)-4-(difluoro...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776300(6-((4R,11R,14aR)-12-chloro-8-((4-(difluoromethyl)-...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776299(3-((4R,14aR)-12-chloro-8-(((S)-2-(difluoromethylen...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776299(3-((4R,14aR)-12-chloro-8-(((S)-2-(difluoromethylen...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776288(1-(isobutyryloxy)ethyl(4R,11S,14aR)-11-(2-amino-3-...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776288(1-(isobutyryloxy)ethyl(4R,11S,14aR)-11-(2-amino-3-...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776287((5aR,6S,9R)-12-(((S)-2-(difluoromethylene)tetrahyd...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776287((5aR,6S,9R)-12-(((S)-2-(difluoromethylene)tetrahyd...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776294(4-((4R,14aR)-12-chloro-10-fluoro-8-(((2R,7aS)-2-fl...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776294(4-((4R,14aR)-12-chloro-10-fluoro-8-(((2R,7aS)-2-fl...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776293(4-((4R,14aR)-12-chloro-8-(((S)-2-(difluoromethylen...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776293(4-((4R,14aR)-12-chloro-8-(((S)-2-(difluoromethylen...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776292(6-((4R,11R,14aR)-12-chloro-8-(((S)-2-(difluorometh...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776292(6-((4R,11R,14aR)-12-chloro-8-(((S)-2-(difluorometh...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776291(3-((4R,11S,14aR)-12-chloro-8-(((S)-2-(difluorometh...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776291(3-((4R,11S,14aR)-12-chloro-8-(((S)-2-(difluorometh...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776249(6-((4R,11S,14aR)-12-chloro-8-(((S)-2-(difluorometh...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776248(6-((4R,11R,14aR)-12-chloro-8-(((S)-2-(difluorometh...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776248(6-((4R,11R,14aR)-12-chloro-8-(((S)-2-(difluorometh...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776246(3-((4R,11R,14aR)-8-(((S)-2-(difluoromethylene)tetr...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776246(3-((4R,11R,14aR)-8-(((S)-2-(difluoromethylene)tetr...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776252(4-((4R,11R,14aR)-8-(((S)-2-(difluoromethylene)tetr...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776250(6-((4R,11R,14aR)-12-chloro-10-fluoro-8-(((2R,7aS)-...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776250(6-((4R,11R,14aR)-12-chloro-10-fluoro-8-(((2R,7aS)-...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776307(4-((4R,14aR)-12-chloro-8-(((S)-2-(difluoromethylen...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776239(6-((4R,11R,14aR)-10,12-difluoro-8-(((2R,7aS)-2-flu...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776238(6-((4R,11S,14aR)-10,12-difluoro-8-(((2R,7aS)-2-flu...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776306(6-((4R,11R,14aR)-12-chloro-10-fluoro-13-methylene-...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776238(6-((4R,11S,14aR)-10,12-difluoro-8-(((2R,7aS)-2-flu...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776303(6-((4R,11R,14aR)-12-chloro-8-((4-(difluoromethylen...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776243(6-((4R,11S,14aR)-8-(((7aS)-2-(difluoromethylene)-t...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776309(6-((4R,11R,14aR)-12-chloro-8-(((1R,7a'S)-2,2-diflu...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776309(6-((4R,11R,14aR)-12-chloro-8-(((1R,7a'S)-2,2-diflu...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776308(6-((4R,11R,14aR)-12-chloro-8-(((1S,7a'S)-2,2-diflu...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776308(6-((4R,11R,14aR)-12-chloro-8-(((1S,7a'S)-2,2-diflu...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776307(4-((4R,14aR)-12-chloro-8-(((S)-2-(difluoromethylen...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776266(6-((4R,11R,14aR)-8-(((S)-2-(difluoromethylene)tetr...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776265(6-((4R,11S,14aR)-8-(((S)-2-(difluoromethylene)tetr...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776264(6-((4R,11S,14aR)-8-(((R)-2-(difluoromethylene)tetr...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776257(2-amino-4-((4R,11R,14aR)-10,12-difluoro-8-(((2R,7a...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776257(2-amino-4-((4R,11R,14aR)-10,12-difluoro-8-(((2R,7a...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

TargetGTPase KRas [G12D]/RAF proto-oncogene serine/threonine-protein kinase(Human)
880 Winter Street, Suite 1003

WIPO
LigandPNGBDBM776256(2-amino-4-((4R,11S,14aR)-10,12-difluoro-8-(((2R,7a...)
Affinity DataIC50: 100nMAssay Description:The test compounds were prepared as lOmM stock solution in 100% DMSO. The stock solution was then serially diluted 3 -fold in 100% DMSO to 10 concent...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025049274

Displayed 1 to 50 (of 137 total ) | Next | Last >>
Jump to: