Reaction Details  Report a problem with these data
Cell Reactant:
Trypsin
Syringe Reactant:
BDBM777
Meas. Tech.:
Isothermal Titration Calorimetry
Entry Date.:
2004-06-15
ΔG°:
-26.3000±0.2000 (kJ/mole)
pH:
8.0000±n/a
Log10Kb:
3.3
Temperature:
303.1500±n/a (K)
ΔH° :
-13.4000±0.6000 (kJ/mole)
ΔHobs :
-13.4000±0.6000 (kJ/mole)
Corrected for ΔHioniz:
not known
ΔS° :
0.0426±0.0023 (kJ/mole-K)
Citation
 Talhout, R; Villa, A; Mark, AE; Engberts, JB Understanding binding affinity: a combined isothermal titration calorimetry/molecular dynamics study of the binding of a series of hydrophobically modified benzamidinium chloride inhibitors to trypsin. J Am Chem Soc 125:10570-9 (2003) [PubMed]  Article
Cell React
Source:
no
Name:
Serine protease 1
Synonyms:
Trypsin | Cationic trypsin | Beta-Trypsin | Trypsin I | TRY1_BOVIN | PRSS1 | TRP1 | TRY1 | TRYP1
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bovine
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Syringe React
Source:
Synthesized
Name:
BDBM777
Synonyms:
benzamidine deriv. | [amino(4-butylphenyl)methylidene]azanium | p-n-butylbenzamidinium chloride
Type:
n/a
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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