Reaction Details  Report a problem with these data
Cell Reactant:
Ephrin type-A receptor 3 ligand binding domain (EphA3-LBD)
Syringe Reactant:
BDBM223311
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2017-04-27
ΔG°:
-30.5500±n/a (kJ/mole)
pH:
6.5000±0.0000
Temperature:
300.1500±0.0000 (K)
ΔH° :
-6.4500±1.3000 (kJ/mole)
ΔS° :
0.0803±0.0000 (kJ/mole-K)
Citation
 Wu, B; De, SK; Kulinich, A; Salem, AF; Koeppen, J; Wang, R; Barile, E; Wang, S; Zhang, D; Ethell, I; Pellecchia, M Potent and Selective EphA4 Agonists for the Treatment of ALS. Cell Chem Biol 24:293-305 (2017) [PubMed]  Article 
Cell React
Name:
Ephrin type-A receptor 3 [29-207]
Synonyms:
EPHA3_HUMAN | EPHA3 | ETK | ETK1 | HEK | TYRO4 | Ephrin type-A receptor 3 ligand binding domain (EphA3-LBD)
Type:
Protein
Mol. Mass.:
20707.76
Organism:
Human
Description:
Human EphA3-LBD (29-207 aa)
Residue:
179
Sequence:
EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVK
  
Syringe React
Name:
BDBM223311
Synonyms:
123C4
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: