Reaction Details 
Report a problem with these data
Report a problem with these dataCell Reactant:
Na+/H+ exchanger regulatory factor-1 PDZ domain (PDZ1)
Syringe Reactant:
BDBM228843
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2017-05-30
ΔG°:
-26.0000±1.0000 (kJ/mole)
pH:
8.0000±0.0000
Log10Kb:
6
Temperature:
298.1500±0.0000 (K)
ΔH° :
-15.9000±0.8000 (kJ/mole)
ΔS° :
0.0340±0.0030 (kJ/mole-K)
Citation
Mamonova, T; Zhang, Q; Chandra, M; Collins, BM; Sarfo, E; Bu, Z; Xiao, K; Bisello, A; Friedman, PA Origins of PDZ Binding Specificity. A Computational and Experimental Study Using NHERF1 and the Parathyroid Hormone Receptor. Biochemistry 56:2584-2593 (2017) [PubMed] Article More Info.:
Cell React
Name:
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 [1-140]
Synonyms:
NHRF1_HUMAN | NHERF1 | NHERF | SLC9A3R1 | Na+/H+ exchanger regulatory factor-1 PDZ domain (PDZ1)
Type:
Protein
Mol. Mass.:
14899.03
Organism:
Human
Description:
PDZ1 domain of human NHERF1 (1-140 aa)
Residue:
140
Sequence:
MSADAAAGAPLPRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPREA
Syringe React
Name:
BDBM228843
Synonyms:
QAAWETVM | PTHRct-8 mutant (QAAWETVM)
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
