Reaction Details  Report a problem with these data
Cell Reactant:
Cyclin-dependent kinase 2
Syringe Reactant:
BDBM225312
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2017-05-10
ΔG°:
-7.88±0.06 (kcal/mole)
Temperature:
298.0000±0.0000 (K)
ΔH° :
-7.25±0.67 (kJ/mole)
ΔS° :
0±0 (kJ/mole-K)
Citation
 D3R, DD CSAR CDK2-CyclinA D3R 219:0 (2015) [PubMed] 
Cell React
Name:
Cyclin-dependent kinase 2
Synonyms:
Cyclin-dependent kinase 2 (CDK2) | p33 protein kinase | CDK2-Kinase | Cell division protein kinase 2 | Protein cereblon/Cyclin-dependent kinase 2 | CDK2_HUMAN | CDK2 | CDKN2
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Human
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Syringe React
Name:
BDBM225312
Synonyms:
CS4
Type:
Small Organic Molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
[O-]C(=O)c1ccc(cc1)C(=O)Nc1cc([nH]n1)C1CC1
Structure:
Search PDB for entries with ligand similarity: