Cell Reactant:
Caseinolytic protein C1 (ClpC1 NTD)
Syringe Reactant:
BDBM213240
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
02/21/17
ΔG°:
-45.09±n/a (kJ/mole)
pH:
7.5±0
Temperature:
298.15±0 (K)
ΔH° :
-39.72±0.24 (kJ/mole)
ΔS° :
0.018±0 (kJ/mole-K)
Citation
 Vasudevan, DRao, SPNoble, CG Structural basis of mycobacterial inhibition by cyclomarin A J Biol Chem 288:30883-91 (2013) [PubMed]  Article
Cell React
Name:
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145]
Synonyms:
Caseinolytic protein C1 (ClpC1 NTD)
Type:
Protein
Mol. Mass.:
15982.24
Organism:
Mycobacterium tuberculosis
Description:
M. tuberculosis ClpC1 N-terminal domain (1-145 aa)
Residue:
145
Sequence:
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGY
  
Syringe React
Name:
BDBM213240
Synonyms:
Cyclomarin A1 (CymA1)
Type:
Small organic molecule
Emp. Form.:
C59H92N10O11
Mol. Mass.:
1117.4222
SMILES:
[#6]-[#8]-[#6@@H](-[#6@@H]-1-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6@@H](-[#6])-[#6]-[#8])-[#7](-[#6])-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7](-[#6])-[#6](=O)-[#6@@H](-[#7]-[#6]-1=O)-[#6](-[#6])-[#6])-[#6@H](-[#6])\[#6]=[#6](/[#6])-[#6])-[#6@H](-[#8])-c1cn(c2ccccc12)C([#6])([#6])[#6@@H](-[#8])-[#6]-[#7]-[#6]-[#6]-[#6]-[#7])-c1ccccc1 |r|
Structure:
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