Reaction Details Report a problem with these data
Cell Reactant:
Ephrin type-A receptor 4 ligand binding domain (I159A-EphA4-LBD)
Syringe Reactant:
BDBM223311
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
04/27/17
ΔG°:
-37.11±n/a (kJ/mole)
pH:
6.5±0
Temperature:
300.15±0 (K)
ΔH° :
-35.7±0.3 (kJ/mole)
ΔS° :
0.0047±0 (kJ/mole-K)
Citation
Wu, B; De, SK; Kulinich, A; Salem, AF; Koeppen, J; Wang, R; Barile, E; Wang, S; Zhang, D; Ethell, I; Pellecchia, M Potent and Selective EphA4 Agonists for the Treatment of ALS. Cell Chem Biol 24:293-305 (2017) [PubMed] Article
More Info.:
Cell React
Name:
Ephrin type-A receptor 4 [29-209,I159A]
Synonyms:
EPHA4 | EPHA4_HUMAN | Ephrin type-A receptor 4 ligand binding domain (I159A-EphA4-LBD) | HEK8 | SEK | TYRO1
Type:
Protein
Mol. Mass.:
20808.36
Organism:
Homo sapiens (Human)
Description:
Human EphA4-LBD I159A mutant
Residue:
181
Sequence:
NEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDAGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVR