Reaction Details Report a problem with these data
Target
Phosphatidylinositol 4-kinase
Ligand
BDBM533766
Substrate
n/a
Meas. Tech.
PI(4)K enzymatic Assay
IC50
<100±n/a nM
Citation
 Michael, YJ; Robert, TM; Peichao, L COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CRYPTOSPORIDIOSIS WIPO 0:0 (2022) [PubMed] 
Target
Name:
Phosphatidylinositol 4-kinase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
128976.50
Organism:
n/a
Description:
Q5CVD3
Residue:
1114
Sequence:
MVEGWLTTSKSMSGLFGKSLISKQKSTSGSINFNDDELTDNIVVDLGDFSNNNNNKSDNLYSRKDSKGGEFDKSKGSLLRLFQSDVFDAHLHLYYIYHHKEFGVHEYLVNLLYERSDEILWYLPQLCEISLNRFEKSSLWKYFLDKSSENMNFSLILSWMYQAMNEDNIPLISEYAQNMLQEIEMAMVNSKLKPDIRYIEKRLYFWRRSNLSVFQSLCNQNMKLNDIEDEFKDNDNTMLMNRENTNTQLSLAIYSTLPSSETINLNESDDLNQDDNNRIISSDINTNTIPNNNSKTIKLSSCDVLPDIWIYRIINDDFSCENKAKIEYIQTKLGLINRQFKNLYSNATCAAYYNPNPGTSLNYKSGVSSSAFGSLNSGFLPTSIISGSSSFGTFSSGGNSNKVSIPYFFFSKLGSPFDLIDVNKIINDIQFRSKSRINLINKSHNFNVQDNSSEDTVSIPKTPRDVIRITHPFSPCSETESETNNLDLDDNGTFEEIKLAPDSNVCSDNDNKKIPILTPNSTKIIECLENLSNENSGSPIQLNDDILRNEEIFKVYISEIEKESETLYYLLKQHRYNYFNRVNQLVSQFLEISNYLQSNINKEHRCEILEFIIEELNLWLFYSRFSISISRTTFLLNSISLPMPSFNNEFCSRFSENDSFNSNNKDGNSKGIIGFSHSDYIMDKGLCSLNNCQFLRIIPNECKIYNSRKRVHFLLAIEIADLDDQDYELGKNSQDLISKDILNYLKNHGIKLKTDNNDENQNRSQDILLNFLNILSVGISESIDMGLSQEDFNQITFIDNKDSDEIEDSSIHDNELSDEDIFINKDWPQETWSSKIKRYRKESPYSKLKSWGIKTLLLKSSDDLRQEYLASQLLQQFDWIFKINKLPLWLHPYEILVIGSHGGFIEYIQDTFSIDSLKRRFQTDNLLNCFDQLFKDEELKSKARKCFVESHAAYSLVSYFLQVKDRHNGNFLIDKHGHIIQIDYGFMLSNSPGNVNFEQSPFKLTQEFLDVMMGENSSDFQYFQQLIIKGFLASRKHVDQIVLTIESMTSASKLPCFSLFTNKEYFIQDIRDRFFLHLTEEQCVVKVTELIQSSINNWRSIQYDAFQRITNGIL
 
Inhibitor
Name:
BDBM533766
Synonyms:
5-(3-(4-Carbamoylphenyl)-N-methylpyrazolo[1,5-a]pyridine-5-carboxamido)-2-chlorobenzoic acid | WO2022079616, Example 1.03
Type:
Small organic molecule
Emp. Form.:
C23H17ClN4O4
Mol. Mass.:
448.858
SMILES:
CN(C(=O)c1ccn2ncc(-c3ccc(cc3)C(N)=O)c2c1)c1ccc(Cl)c(c1)C(O)=O
Structure:
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