Reaction Details Report a problem with these data
Target
External core antigen
Ligand
BDBM576345
Substrate
n/a
Meas. Tech.
PHH Natural Infection Assay
IC50
1192±n/a nM
Citation
 Hongying, Y; Bo, Z; Xiufang, Z AROMATIC BRIDGED RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION WIPO WO2022112205 Publication Date -1/2/2022 
Target
Name:
External core antigen
Synonyms:
C | HBEAG_HBVGB | HBeAg | Precore protein | p25
Type:
Protein
Mol. Mass.:
24103.68
Organism:
HBVgbn
Description:
P89951
Residue:
212
Sequence:
MQLFHLCLIISCSCPTVQASKLCLGWLLGMDIDPYKEFGASVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPNHTALRQAVLCWGELMTGCSWVGNNLEDPASRELVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSPASQC
  
Inhibitor
Name:
BDBM576345
Synonyms:
WO2022112205, Example 2-a
Type:
Small organic molecule
Emp. Form.:
C18H15ClN2O4S
Mol. Mass.:
390.841
SMILES:
C[S@](=O)c1ccc(o1)C(=O)NC12CC(C1)(C2)c1nc2cc(Cl)ccc2o1 |r|
Structure:
Search PDB for entries with ligand similarity: