Reaction Details Report a problem with these data
Target
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Ligand
BDBM50231824
Substrate
n/a
Meas. Tech.
Apoptosis Inhibition Assay
EC50
<100000±n/a nM
Citation
 Zhang, Z; Wang, X; Huang, S; Jiang, X; Li, L; Zhang, Z; Han, J Apoptosis inhibitors US Patent  US11725000 Publication Date 8/15/2023 
Target
Name:
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Synonyms:
1.3.5.1 | Iron-sulfur subunit of complex II | SDH | SDH1 | SDHB | SDHB_HUMAN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Type:
PROTEIN
Mol. Mass.:
31643.02
Organism:
Homo sapiens (Human)
Description:
ChEMBL_117429
Residue:
280
Sequence:
MAAVVALSLRRRLPATTLGGACLQASRGAQTAAATAPRIKKFAIYRWDPDKAGDKPHMQTYEVDLNKCGPMVLDALIKIKNEVDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTNLNKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQEGKQQYLQSIEEREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKEKKASV
  
Inhibitor
Name:
BDBM50231824
Synonyms:
CHEMBL4089190 | US11725000, Compound 41
Type:
Small organic molecule
Emp. Form.:
C9H7N5O2S2
Mol. Mass.:
281.314
SMILES:
CS(=O)(=O)c1nc(cc(n1)-c1cccs1)N=[N+]=[N-]
Structure:
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