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Target
Glucagon-like peptide 1 receptor
Ligand
BDBM620508
Substrate
n/a
Meas. Tech.
The Alizarin Assay (ARS) (Glucose)
Kd
3200000±n/a nM
Citation
 Kruse, T; Kofod-Hansen, M; Muenzel, MW; Thoegersen, H; Sauerberg, P; Rasmussen, JE; Behrens, C; Hoeg-Jensen, T; Balsanek, V; Drobnakova, Z; Droz, L; Havranek, M; Kotek, V; Stengl, M; Snajdr, I; Drusanova, H Glucose-sensitive albumin-binding derivatives US Patent  US11767332 Publication Date 9/26/2023 
Target
Name:
Glucagon-like peptide 1 receptor
Synonyms:
GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1)
Type:
Enzyme
Mol. Mass.:
53035.78
Organism:
Homo sapiens (Human)
Description:
P43220
Residue:
463
Sequence:
MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
  
Inhibitor
Name:
BDBM620508
Synonyms:
N6-(4-Borono-2-fluorobenzoyl)-N2-(6-fluoro-1-hydroxy-1,3-dihydrobenzo[c][1,2] oxaborole-5-carbonyl)-L-lysine | US11767332, Example 14
Type:
Small organic molecule
Emp. Form.:
C21H22B2F2N2O8
Mol. Mass.:
490.027
SMILES:
OB(O)c1ccc(C(=O)NCCCC[C@H](NC(=O)c2cc3COB(O)c3cc2F)C(O)=O)c(F)c1 |r|
Structure:
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