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Target
Monoacylglycerol lipase ABHD6 [33-337]
Ligand
BDBM645021
Substrate
n/a
Meas. Tech.
Evaluation of ABHD6 Enzyme Inhibitory Activity Assay
IC50
2.00±n/a nM
Citation
 YOSHIDA, A; HYAKUTAKE, R; NAGASHIMA, N; MISU, R; MORI, S ABHD6 ANTAGONIST US Patent  US20240010658 Publication Date 1/11/2024 
Target
Name:
Monoacylglycerol lipase ABHD6 [33-337]
Synonyms:
Monoacylglycerol lipase ABHD6 (33-337)
Type:
Enzyme
Mol. Mass.:
34939.75
Organism:
Human
Description:
Q9BV23[33-337]
Residue:
305
Sequence:
ALIRIYYWYWRRTLGMQVRYVHHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSSLCLVCPAGLQYSTDNQFVQRLKELQGSAAVEKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNNFYRKLFLEIVSEKSRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGADMLAKSIANCQVELLENCGHSVVMERPRKTAKLIIDFLASVHNTDNNKKLD
  
Inhibitor
Name:
BDBM645021
Synonyms:
US11981682, Example 3-6 | US20240010658, Example 3-6
Type:
Small organic molecule
Emp. Form.:
C20H21BrN6OS
Mol. Mass.:
473.389
SMILES:
Brc1ccc(N[C@@H]2CC[C@H]3CN(C[C@@H]23)C(=O)c2cc3nn4CCCc4c3s2)nn1 |r|
Structure:
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