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Target
Cystathionine gamma-lyase
Ligand
BDBM330320
Substrate
n/a
Meas. Tech.
In Vitro Assay
IC50
<10000±n/a nM
Citation
 Durón, SG; Chapman, J; Sydserff, SG; Rao, SG; Stein, G; Wade, W Cystathionine-γ-lyase (CSE) inhibitors US Patent  US9725426 Publication Date 8/8/2017 
Target
Name:
Cystathionine gamma-lyase
Synonyms:
CGL_HUMAN | CTH | Cystathionine gamma-lyase (CSE) | Cysteine-protein sulfhydrase | Gamma-cystathionase
Type:
Protein
Mol. Mass.:
44509.52
Organism:
Homo sapiens (Human)
Description:
P32929
Residue:
405
Sequence:
MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS
  
Inhibitor
Name:
BDBM330320
Synonyms:
US9725426, 24
Type:
Small organic molecule
Emp. Form.:
C6H10N6
Mol. Mass.:
166.1838
SMILES:
C1CCC(C1)=NNc1nnn[nH]1 |(3.47,-2.4,;4.37,-1.16,;3.47,.09,;2,-.39,;2,-1.93,;.67,.38,;-.67,-.39,;-2,.38,;-3.47,-.09,;-4.37,1.15,;-3.47,2.4,;-2,1.92,)|
Structure:
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