Target

Ligand

Substrate

Meas. Tech.

Human A1 Adenosine Receptor Binding Assay

Ki

833±n/a nM

Citation

 Cosimelli, B; Greco, G; Ehlardo, M; Novellino, E; Da Settimo, F; Taliani, S; La Motta, C; Bellandi, M; Tuccinardi, T; Martinelli, A; Ciampi, O; Trincavelli, ML; Martini, C Derivatives of 4-Amino-6-hydroxy-2-mercaptopyrimidine as Novel, Potent, and Selective A3 Adenosine Receptor Antagonists. J Med Chem 51:1764-70 (2008) [PubMed]  Article Copy BDB DOI

More Info.:

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Name:

Adenosine receptor A2a

Synonyms:

A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)

Type:

G Protein-Coupled Receptor (GPCR)

Mol. Mass.:

44716.46

Organism:

Homo sapiens (Human)

Description:

P29274

Residue:

412

Sequence:

MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS

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Blast E-value cutoff:

Name:

BDBM21217

Synonyms:

2-(4-methyl-1H-1,3-benzodiazol-2-yl)quinoxaline | CHEMBL198779 | benzimidazole-quinoxaline, C3

Type:

Small organic molecule

Emp. Form.:

C16H12N4

Mol. Mass.:

260.2933

SMILES:

Cc1cccc2[nH]c(nc12)-c1cnc2ccccc2n1

Structure:

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Similarity to this molecule at least:

Name:

BDBM21241

Synonyms:

Adenosine, N6-Ethyl-carboxamido | Adenosine-5 -(N-ethylcarboxamide) | N-Ethylcarboxamidoadenosine | [3H]NECA

Type:

n/a

Emp. Form.:

n/a

Mol. Mass.:

n/a

SMILES:

n/a

Structure: