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Target
Mevalonate kinase
Ligand
BDBM38696
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
>9999000±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38696
Synonyms:
2-[4-(2,4-dimethoxybenzyl)piperazino]pyrimidine | 2-[4-[(2,4-dimethoxyphenyl)methyl]-1-piperazinyl]pyrimidine | 2-[4-[(2,4-dimethoxyphenyl)methyl]piperazin-1-yl]pyrimidine | MLS000105277 | SMR000102158 | cid_199200
Type:
Small organic molecule
Emp. Form.:
C17H22N4O2
Mol. Mass.:
314.3822
SMILES:
COc1ccc(CN2CCN(CC2)c2ncccn2)c(OC)c1
Structure:
Search PDB for entries with ligand similarity: