Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM39558
Substrate
n/a
Meas. Tech.
Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1)
EC50
>99000±n/a nM
Citation
 PubChem, PC Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) PubChem Bioassay (2007)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM39558
Synonyms:
2-(6-keto-1-phenyl-pyridazin-3-yl)oxypropionic acid butyl ester | 2-[(6-oxo-1-phenyl-3-pyridazinyl)oxy]propanoic acid butyl ester | MLS000114711 | SMR000092049 | butyl 2-(6-oxidanylidene-1-phenyl-pyridazin-3-yl)oxypropanoate | butyl 2-(6-oxo-1-phenylpyridazin-3-yl)oxypropanoate | cid_4619761
Type:
Small organic molecule
Emp. Form.:
C17H20N2O4
Mol. Mass.:
316.3517
SMILES:
CCCCOC(=O)C(C)Oc1ccc(=O)n(n1)-c1ccccc1
Structure:
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