Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 4 group A member 1
Ligand
BDBM40668
Substrate
n/a
Meas. Tech.
High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters
IC50
783.41±122 nM
Citation
 PubChem, PC High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters PubChem Bioassay (2008)[AID] 
Target
Name:
Nuclear receptor subfamily 4 group A member 1
Synonyms:
GFRP1 | HMR | NAK1 | NR4A1 | NR4A1_HUMAN | nuclear receptor subfamily 4, group A, member 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
64467.13
Organism:
Homo sapiens (Human)
Description:
gi_27894344
Residue:
598
Sequence:
MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
  
Inhibitor
Name:
BDBM40668
Synonyms:
2-(2,5-dimethyl-1-pyrrolyl)-3-thiophenecarboxylic acid | 2-(2,5-dimethyl-1H-pyrrol-1-yl)-3-thiophenecarboxylic acid | 2-(2,5-dimethylpyrrol-1-yl)-3-thenoic acid | 2-(2,5-dimethylpyrrol-1-yl)thiophene-3-carboxylic acid | MLS000544899 | SMR000126656 | cid_2808627
Type:
Small organic molecule
Emp. Form.:
C11H11NO2S
Mol. Mass.:
221.276
SMILES:
Cc1ccc(C)n1-c1sccc1C(O)=O |(10.55,1.2,;9.09,1.68,;8.61,3.14,;7.07,3.14,;6.6,1.68,;5.13,1.2,;7.84,.77,;7.84,-.77,;9.09,-1.68,;8.61,-3.14,;7.07,-3.14,;6.6,-1.68,;5.13,-1.2,;3.99,-2.23,;4.81,.31,)|
Structure:
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