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Target
Mothers against decapentaplegic homolog 3
Ligand
BDBM41973
Substrate
n/a
Meas. Tech.
SMAD Transcription Factor Inhibitors Secondary Dose Response Confirmation
IC50
>40000±n/a nM
Citation
 PubChem, PC SMAD Transcription Factor Inhibitors Secondary Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Mothers against decapentaplegic homolog 3
Synonyms:
MADH3 | SMAD3 | SMAD3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48085.78
Organism:
Homo sapiens (Human)
Description:
gi_5174513
Residue:
425
Sequence:
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS
  
Inhibitor
Name:
BDBM41973
Synonyms:
6-[(2,4-dimethoxyphenyl)-(1-piperidinyl)methyl]-1,3-benzodioxol-5-ol | 6-[(2,4-dimethoxyphenyl)-piperidin-1-yl-methyl]-1,3-benzodioxol-5-ol | 6-[(2,4-dimethoxyphenyl)-piperidin-1-ylmethyl]-1,3-benzodioxol-5-ol | 6-[(2,4-dimethoxyphenyl)-piperidino-methyl]sesamol | cid_340202
Type:
Small organic molecule
Emp. Form.:
C21H25NO5
Mol. Mass.:
371.4269
SMILES:
COc1ccc(C(N2CCCCC2)c2cc3OCOc3cc2O)c(OC)c1
Structure:
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