Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM38079
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition
IC50
22560±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM38079
Synonyms:
5-(4-fluorophenyl)-4-(1-methyltetrazol-5-yl)sulfanylthieno[2,3-d]pyrimidine | 5-(4-fluorophenyl)-4-[(1-methyl-1,2,3,4-tetrazol-5-yl)sulfanyl]thieno[2,3-d]pyrimidine | 5-(4-fluorophenyl)-4-[(1-methyl-5-tetrazolyl)thio]thieno[2,3-d]pyrimidine | 5-(4-fluorophenyl)-4-[(1-methyltetrazol-5-yl)thio]thieno[2,3-d]pyrimidine | MLS000058474 | SMR000068062 | cid_2526122
Type:
Small organic molecule
Emp. Form.:
C14H9FN6S2
Mol. Mass.:
344.39
SMILES:
Cn1nnnc1Sc1ncnc2scc(-c3ccc(F)cc3)c12
Structure:
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