Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43535
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition
IC50
14570±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Human
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43535
Synonyms:
(6,7-dimethoxyquinazolin-4-yl)-homoveratryl-amine | MLS000721156 | N-(3,4-dimethoxyphenethyl)-6,7-dimethoxy-4-quinazolinamine | N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-4-quinazolinamine | N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-quinazolin-4-amine | N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxyquinazolin-4-amine | SMR000335336 | cid_1490260
Type:
Small organic molecule
Emp. Form.:
C20H23N3O4
Mol. Mass.:
369.4143
SMILES:
COc1ccc(CCNc2ncnc3cc(OC)c(OC)cc23)cc1OC
Structure:
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