Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM47883
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM47883
Synonyms:
5-bromanyl-N'-[(Z)-(2-oxidanylidenenaphthalen-1-ylidene)methyl]pyridine-3-carbohydrazide | 5-bromo-N'-[(Z)-(2-keto-1-naphthylidene)methyl]nicotinohydrazide | 5-bromo-N'-[(Z)-(2-oxo-1-naphthalenylidene)methyl]-3-pyridinecarbohydrazide | 5-bromo-N'-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]pyridine-3-carbohydrazide | MLS001185481 | SMR000502115 | cid_5719283
Type:
Small organic molecule
Emp. Form.:
C17H12BrN3O2
Mol. Mass.:
370.2
SMILES:
Oc1ccc2ccccc2c1C=NNC(=O)c1cncc(Br)c1 |w:12.14|
Structure:
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