Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM76039
Substrate
n/a
Meas. Tech.
SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 3
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of agonists of the Cannabinoid Receptor 2 using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM76039
Synonyms:
2,3-dihydro-1,4-benzodioxin-6-yl-[4-(2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)-1-piperazinyl]methanone | 2,3-dihydro-1,4-benzodioxin-6-yl-[4-(2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]methanone | 2,3-dihydro-1,4-benzodioxin-6-yl-[4-(2-methyl-5,6,7,8-tetrahydrobenzothiopheno[2,3-d]pyrimidin-4-yl)piperazino]methanone | MLS-0437137.0001 | cid_1434989
Type:
Small organic molecule
Emp. Form.:
C24H26N4O3S
Mol. Mass.:
450.553
SMILES:
Cc1nc(N2CCN(CC2)C(=O)c2ccc3OCCOc3c2)c2c3CCCCc3sc2n1
Structure:
Search PDB for entries with ligand similarity: