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Target
Bcl-2-related protein A1
Ligand
BDBM46584
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
12400±207 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM46584
Synonyms:
2-N,4-N-dibenzylquinazoline-2,4-diamine;hydrochloride | MLS000769571 | N*2*,N*4*-Dibenzyl-quinazoline-2,4-diamine | N2,N4-bis(phenylmethyl)quinazoline-2,4-diamine;hydrochloride | SMR000434303 | benzyl-[2-(benzylamino)quinazolin-4-yl]amine;hydrochloride | cid_16472035
Type:
Small organic molecule
Emp. Form.:
C22H20N4
Mol. Mass.:
340.421
SMILES:
C(Nc1nc(NCc2ccccc2)c2ccccc2n1)c1ccccc1
Structure:
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