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Target
Bcl-2-related protein A1
Ligand
BDBM76133
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
11400±473 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM76133
Synonyms:
MLS001207566 | N-(2,4-Dimethoxy-benzylidene)-N'-(6-methoxy-2-methyl-quinolin-4-yl)-hydrazine | N-[(2,4-dimethoxyphenyl)methylideneamino]-6-methoxy-2-methyl-4-quinolinamine | N-[(2,4-dimethoxyphenyl)methylideneamino]-6-methoxy-2-methyl-quinolin-4-amine | N-[(2,4-dimethoxyphenyl)methylideneamino]-6-methoxy-2-methylquinolin-4-amine | SMR000517672 | [(2,4-dimethoxybenzylidene)amino]-(6-methoxy-2-methyl-4-quinolyl)amine | cid_3141523
Type:
Small organic molecule
Emp. Form.:
C20H21N3O3
Mol. Mass.:
351.399
SMILES:
COc1ccc(CN=Nc2cc(C)nc3ccc(OC)cc23)c(OC)c1 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: