Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM81925
Substrate
n/a
Ki
6.4±n/a nM
Comments
PDSP_2952
Citation
 Klotz, KN; Vogt, H; Tawfik-Schlieper, H Comparison of A1 adenosine receptors in brain from different species by radioligand binding and photoaffinity labelling. Naunyn Schmiedebergs Arch Pharmacol 343:196-201 (1991) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RABIT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine receptor A1 (A1)
Type:
Enzyme
Mol. Mass.:
36566.33
Organism:
Oryctolagus cuniculus (Rabbit)
Description:
P34970
Residue:
328
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPETYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKAVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLREVQRAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRRQLSKKASASSGDPHKYYGKELKIAKSLALILFLFALSWLPLHILNCVTLFCPSCQKPSILVYTAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCRPAPAGDGDEDLPEEKPND
  
Inhibitor
Name:
BDBM81925
Synonyms:
8-Cyclopentyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione | 8-Cyclopentyltheophylline (CPT) | CAS_1917 | CHEMBL106265 | CPT | NSC_1917
Type:
Small organic molecule
Emp. Form.:
C12H16N4O2
Mol. Mass.:
248.281
SMILES:
Cn1c2nc([nH]c2c(=O)n(C)c1=O)C1CCCC1
Structure:
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