Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM81928
Substrate
n/a
Ki
9±n/a nM
Comments
PDSP_1614
Citation
 Tahraoui, L; Floch, A; Cavero, I Functional validation of platelet-activating factor receptor sites characterized biochemically by a specific and reproducible [3H]platelet-activating factor binding in human platelets. J Pharmacol Exp Ther 252:1221-7 (1990) [PubMed] 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39219.60
Organism:
Homo sapiens (Human)
Description:
PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:
342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
  
Inhibitor
Name:
BDBM81928
Synonyms:
1H,3H-Pyrrolo[1,2-c]thiazole-7-carboxamide,N-(3-benzoylphenyl)-3-(3-pyridinyl)- | CAS_122570-29-0 | RP 58467
Type:
Small organic molecule
Emp. Form.:
C25H19N3O2S
Mol. Mass.:
425.502
SMILES:
O=C(Nc1ccc(cc1)C(=O)c1ccccc1)c1ccn2C(SCc12)c1cccnc1
Structure:
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